CD63 antibody [MEM-259] (PE-Cy5)
Referencia GTX28219-09-100test
embalaje : 100test
Marca : Genetex
Contact local distributor :
Teléfono : +1 850 650 7790
Host | Mouse |
|---|---|
Clonality | Monoclonal |
Clone Name | MEM-259 |
Isotype | IgG1 |
Application | FACS |
Reactivity | Human |
| Package | 100 test |
Datasheet File View product citations for antibody GTX28219-09 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application | Recommended Dilution |
|---|---|
| FACS | 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension |
Not tested in other applications.
Calculated MW
26 kDa. ( Note )
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
HPB-ALL T cell line
Purification
Purified by size-exclusion chromatography
Conjugation
Phycoerythrin-Cyanine5 (PE-Cy5)
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.
TARGET
Synonyms
CD63 , CD63 molecule , LAMP3 , ME491 , MLA1 , OMA81H , TSPAN30
Cellular Localization
Cell membrane,Lysosome membrane,Late endosome membrane,Endosome,Multivesicular body,Melanosome
Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
Database
Clone Reference
Lanna A et al. Nat Cell Biol 2022; 24 (10):1461-1474 An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory.
Cheng Zhang et al. J Extracell Vesicles 2022; 11 (4):e12209 Plasma extracellular vesicle derived protein profile predicting and monitoring immunotherapeutic outcomes of gastric cancer.
Peng X et al. Biochim Biophys Acta Mol Cell Res 2021; 1868 (1):118857 IKKβ activation promotes amphisome formation and extracellular vesicle secretion in tumor cells.
Lenzini S et al. ACS Nano 2021; 15 (11):17439-17452 Cell-Matrix Interactions Regulate Functional Extracellular Vesicle Secretion from Mesenchymal Stromal Cells.
Huang C.C. et al. Microfluidics and Nanofluidics 2021; 25 A miniaturized, DNA-FET biosensor-based microfluidic system for quantification of two breast cancer biomarkers.
Submit a Reference REVIEW
Clone Reference
Lanna A et al. Nat Cell Biol 2022; 24 (10):1461-1474 An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory.
Cheng Zhang et al. J Extracell Vesicles 2022; 11 (4):e12209 Plasma extracellular vesicle derived protein profile predicting and monitoring immunotherapeutic outcomes of gastric cancer.
Peng X et al. J Exp Clin Cancer Res 2021; 40 (1):183 LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation.
Peng X et al. Biochim Biophys Acta Mol Cell Res 2021; 1868 (1):118857 IKKβ activation promotes amphisome formation and extracellular vesicle secretion in tumor cells.
Lenzini S et al. ACS Nano 2021; 15 (11):17439-17452 Cell-Matrix Interactions Regulate Functional Extracellular Vesicle Secretion from Mesenchymal Stromal Cells.
Huang C.C. et al. Microfluidics and Nanofluidics 2021; 25 A miniaturized, DNA-FET biosensor-based microfluidic system for quantification of two breast cancer biomarkers.
Yang L et al. Mol Cancer 2019; 18 (1):78 Long non-coding RNA HOTAIR promotes exosome secretion by regulating RAB35 and SNAP23 in hepatocellular carcinoma.
Raulf N et al. Eur J Cancer 2018; 102:52-68 Annexin A1 regulates EGFR activity and alters EGFR-containing tumour-derived exosomes in head and neck cancers.
Jakhria T et al. J Biol Chem 2014; β2-microglobulin Amyloid Fibrils are Nanoparticles that Disrupt Lysosomal Membrane Protein Trafficking and Inhibit Protein Degradation by Lysosomes.
| SDS | |
|---|---|
| PBS.pdf | |
| Sodium Azide.pdf | |