CGRP antibody [4901]
Referencia GTX82726-100ul
embalaje : 100ul
Marca : Genetex
Contact local distributor :
Teléfono : +1 850 650 7790
![Anti-CGRP antibody [4901] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX82726](http://www.genetex.com/templates/default/js/lightbox/images/loading.gif "Anti-CGRP antibody [4901] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX82726")
Host | Mouse |
|---|---|
Clonality | Monoclonal |
Clone Name | 4901 |
Isotype | IgG2a |
Application | WB, ICC/IF, IHC-Fr, ELISA, IHC, Neutralizing/Inhibition, RIA |
Reactivity | Human, Mouse, Rat, Dog |
| Package | 100 μl |
Datasheet File View product citations for antibody GTX82726 on CiteAb
APPLICATION
Application Note
Optimal working dilutions should be determined experimentally by the end user.
Calculated MW
15 kDa. ( Note )
PROPERTIES
Form
Liquid
Buffer
10mM HEPES, 150mM NaCl, 0.01% BSA, 50% Glycerol
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Rat
Immunogen
Purified rat alpha-CGRP
Purification
Protein G purified
Conjugation
Unconjugated
RRID
AB_11173100
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Calcitonin-Related Polypeptide Alpha , Cal6 , Cgrp , Cal1 , Calc , Ratcal6 , Calcitonin , Calca
Background
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.
DATA IMAGES
| | GTX82726 ICC/IF ImageImmunostaining of CGRP (red) in cryopreserved DRG neurons grown on coverslips. 40xmag. Green staining is PGP9.5. Yellow staining is the colocalization of CGRP and PGP9.5. |
Application Reference
Li L et al. Brain Behav Immun 2021; 98 : 265-282 KDM6B epigenetically regulated-interleukin-6 expression in the dorsal root ganglia and spinal dorsal horn contributes to the development and maintenance of neuropathic pain following peripheral nerve injury in male rats.
Application : IHC-Fr
Reactivity : Rat
Clone Reference
J Meng et al. J Allergy Clin Immunol 2018; 141 (5):1677-1689.e8 New mechanism underlying IL-31–induced atopic dermatitis
Application : ICC/IF
Reactivity : Mouse
Hashimoto M et al. Front Neural Circuits 2018; 12 (6) Anatomical Evidence for a Direct Projection from Purkinje Cells in the Mouse Cerebellar Vermis to Medial Parabrachial Nucleus
Application : IHC-Fr
Reactivity : Mouse
SL Holtz et al. J Comp Neurol. 2015; 523 (1):139–161 Morphology and Connectivity of Parabrachial and Cortical Inputs to Gustatory Thalamus in Rats
Application : RIA
B Waber-Wenger et al. Histochem Cell Biol 2014; 142 (4):433-47 Sensory innervation of the dorsal longitudinal ligament and the meninges in the lumbar spine of the dog
Submit a Reference Reactivity : Dog
REVIEW
Application Reference
Li L et al. Brain Behav Immun 2021; 98:265-282 KDM6B epigenetically regulated-interleukin-6 expression in the dorsal root ganglia and spinal dorsal horn contributes to the development and maintenance of neuropathic pain following peripheral nerve injury in male rats.
Application : IHC-Fr
Reactivity : Rat
Fang Z et al. PLoS One 2013; 8 (8):e72738 Effect of CGRP-adenoviral vector transduction on the osteoblastic differentiation of rat adipose-derived stem cells.
Application : WB
Reactivity : Human
Clone Reference
J Meng et al. J Allergy Clin Immunol 2018; 141 (5):1677-1689.e8 New mechanism underlying IL-31–induced atopic dermatitis
Application : ICC/IF
Reactivity : Mouse
Hashimoto M et al. Front Neural Circuits 2018; 12 (6) Anatomical Evidence for a Direct Projection from Purkinje Cells in the Mouse Cerebellar Vermis to Medial Parabrachial Nucleus
Application : IHC-Fr
Reactivity : Mouse
SL Holtz et al. J Comp Neurol. 2015; 523 (1):139–161 Morphology and Connectivity of Parabrachial and Cortical Inputs to Gustatory Thalamus in Rats
Application : RIA
B Waber-Wenger et al. Histochem Cell Biol 2014; 142 (4):433-47 Sensory innervation of the dorsal longitudinal ligament and the meninges in the lumbar spine of the dog
Reactivity : Dog
KE Bowler et al. Neuroscience 2013; 228:271-82 Evidence for anti-inflammatory and putative analgesic effects of a monoclonal antibody to calcitonin gene-related peptide
Application : Neutralizing/Inhibition
J Zeller et al. Br J Pharmacol 2008; 155 (7):1093-103 CGRP function-blocking antibodies inhibit neurogenic vasodilatation without affecting heart rate or arterial blood pressure in the rat
Application : ELISA
HC Wong et al. Hybridoma 1993; 12 (1):93-106 Monoclonal Antibody to Rat a-CGRP: Production, Characterization, and In Vivo Immunoneutralization Activity
Application : IHC
Reactivity : Dog
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| Glycerol.pdf | |