Human Calpain S2 (CAPNS2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CAPNS2
Locus ID	84290
Kit Components	GA113487G1, Calpain S2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113487G2, Calpain S2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113487G3, Calpain S2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_032330
UniProt ID	Q96L46
Synonyms	MGC12536; MGC14804
Summary	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.[UniProtKB/Swiss-Prot Function]