Mouse Vldlr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Vldlr
Locus ID	22359
Kit Components	GA204604G1, Vldlr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204604G2, Vldlr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204604G3, Vldlr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001161420, NM_001347441, NM_013703
UniProt ID	P98156
Synonyms	AA408956; AI451093; AW047288
Summary	Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.[UniProtKB/Swiss-Prot Function]