SMARCA2 antibody - middle region
Referencia ARP34484_P050
embalaje : 100ul
Marca : Aviva Systems Biology
SMARCA2 Antibody - middle region (ARP34484_P050)
| Datasheets/Manuals | Printable datasheet for anti-SMARCA2, SMARCA4 (ARP34484_P050) antibody |
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| Tested Species Reactivity | Human |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB, IHC |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human SMARCA2 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: VINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKY |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-SMARCA2, SMARCA4 (ARP34484_P050) antibody is Catalog # AAPY00506 |
| Specificity | 100% homologous to both isoforms of SMARCA2 and all 5 isoforms of SMARCA4 |
| Reference | Muchardt,C., et al., (1994) Mamm. Genome 5 (4), 241-242 |
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| Gene Symbol | SMARCA2 |
| Gene Full Name | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 and 4 |
| Alias Symbols | BRM, SNF2, SWI2, hBRM, NCBRS, Sth1p, BAF190, SNF2L2, SNF2LA, hSNF2a |
| NCBI Gene Id | 6595; 6597 |
| Description of Target | SMARCA2 is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. |
| Uniprot ID | P51531, P51532 |
| Protein Size (# AA) | 278 |
| Molecular Weight | 32kDa |
| Protein Interactions | SDCBP; BEND7; UBC; SMURF2; EED; BMI1; SOX2; UL29; tat; SS18; SSX2; EPAS1; ARID1A; CBX5; PSMB2; ACTL6A; ARID1B; SEPT11; PHF10; NCOR1; SEC22B; SLC9A3R2; TOP2B; SMARCE1; SMARCD3; SMARCD2; SMARCD1; SMARCC2; SMARCC1; SMARCB1; SMARCA4; BMX; CEBPB; SIRT7; DPF1; |
