Wnt pathway inhibitor 3 [663213-98-7]
Referencia NB-64-42469-25mg
embalaje : 25mg
Marca : Neo Biotech
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Wnt pathway inhibitor 3
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Catalog No. T77502 Copy Product Info
Purity: 99.94%
Wnt pathway inhibitor 3 is a potent AC1 inhibitor (IC50: 45 nM) with antiproliferative activity, suitable for studies to ameliorate osteoarthritis in a mouse model of experimental osteoarthritis.
Cas No. 663213-98-7
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Purity:99.94%
Appearance:Solid
Color:White
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Product Information
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Wnt pathway inhibitor 3 is a potent AC1 inhibitor (IC50: 45 nM) with antiproliferative activity, suitable for studies to ameliorate osteoarthritis in a mouse model of experimental osteoarthritis. |
| Targets & IC50 | AC type I:45 nM |
| In vitro | Wnt pathway inhibitor 3 (compound 41) (0-100 μM; 72 h) exhibited anti-proliferative activity with IC50 values of 641, 470, 551, and 618 nM for HS68, Dld1, HCT116, and SW480 cells, respectively.[1] |
| Molecular Weight | 457.27 |
| Formula | C21H17BrN2O5 |
| Cas No. | 663213-98-7 |
| Smiles | C(#N)C=1C(C2=C(C=C3C(=C2)OCO3)OC1N)C4=CC(OC)=C(OCC=C)C(Br)=C4 |
| Relative Density. | 1.59 g/cm3 (Predicted) |
| Storage | Keep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (131.21 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||