Corticotropin-releasing factor (human) (acetate)
Referencia T37111-1mg
embalaje : 1mg
Marca : TargetMol
Corticotropin-releasing factor (human) (acetate)
Copy Product InfoHuman CRF acetate is a chemical compound that effectively stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Information
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Human CRF acetate is a chemical compound that effectively stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary. |
| In vitro | CRF enhances the excitability of type II dlBNST neurons via the activation of the AC-cAMP-PKA pathway, leading to pain-induced aversive responses[1]. |
| In vivo | In rats that received an injection of CRF (1 nmol/side), the duration spent in the drug-paired compartment during the test session (314±22 s) was significantly reduced compared to the time spent in the same compartment during the preconditioning session (520±18 s)[1]. |
| Relative Density. | no data available |
| Sequence | H-{DL-Ser}-{DL-Glu}-{DL-Glu}-{DL-Pro}-{DL-Pro}-{DL-xiIle}-{DL-Ser}-{DL-Leu}-{DL-Asp}-{DL-Leu}-{DL-xiThr}-{DL-Phe}-{DL-His}-{DL-Leu}-{DL-Leu}-{DL-Arg}-{DL-Glu}-{DL-Val}-{DL-Leu}-{DL-Glu}-{DL-Met}-{DL-Ala}-{DL-Arg}-{DL-Ala}-{DL-Glu}-{DL-Gln}-{DL-Leu}-{DL-Ala}-{DL-Gln}-{DL-Gln}-{DL-Ala}-{DL-His}-{DL-Ser}-{DL-Asn}-{DL-Arg}-{DL-Lys}-{DL-Leu}-{DL-Met}-{DL-Glu}-{DL-xiIle}-{DL-xiIle}-NH₂ |
| Sequence Short | SEEPPXSLDLXFHLLREVLEMARAEQLAQQAHSNRKLMEXX |
| Storage | Store under nitrogen,Keep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |