Human GST3 (GSTP1) activation kit by CRISPRa

CAT#: GA101997

GSTP1 CRISPRa kit - CRISPR gene activation of human glutathione S-transferase pi 1



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol GSTP1
Locus ID 2950
Kit Components

GA101997G1, GST3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101997G2, GST3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101997G3, GST3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000852
UniProt ID P09211
Synonyms DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI
Summary Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]

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