Human MGST2 activation kit by CRISPRa

CAT#: GA102903

MGST2 CRISPRa kit - CRISPR gene activation of human microsomal glutathione S-transferase 2



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol MGST2
Locus ID 4258
Kit Components

GA102903G1, MGST2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102903G2, MGST2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102903G3, MGST2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001204366, NM_001204367, NM_001204368, NM_002413
UniProt ID Q99735
Synonyms GST2; MGST-II
Summary The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2011]

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