General Information
| Short Description | Mouse monoclonal anti-Mast Cell Tryptase for use in WB, IHC-P, IHC-F, ELISA and IF in Human, Cat, Dog, Monkey and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IHC-F/ELISA/IF |
| Host | Mouse |
| Reactivity | Human/Cat/Dog/Monkey/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AA1 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1.0 mg/mL |
| Formulation | PBS with 0.09% sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Human mast cell tryptase purified from human lung tissue. |
Additional Info
| Background | Mouse anti Human mast cell tryptase, clone AA1 recognizes human mast cell tryptase, both alpha and beta isoforms. Mouse anti Mast cell tryptase, clone AA1 is an excellent marker for mast cells, and does not bind to any other cell type in immunohistology (Walls et al. 1990).Tryptases are the products of a number of genes and form the major neutral protease present in mast cells secreted in response to infection and injury. Mast cell tryptase has an important role in the pathology of inflammatory diseases, especially asthma through bronchoconstriction (Zhang and Timmerman 1997). |
Information sourced from Uniprot.org