Human Zinc finger MIZ domain containing protein 1 (ZMIZ1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZMIZ1
Locus ID	57178
Kit Components	GA111428G1, Zinc finger MIZ domain containing protein 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111428G2, Zinc finger MIZ domain containing protein 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111428G3, Zinc finger MIZ domain containing protein 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_020338
UniProt ID	Q9ULJ6
Synonyms	hZIMP10; MIZ; RAI17; TRAFIP10; ZIMP10
Summary	This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]