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DL-Tyrosine [556-03-6]

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Référence NB-64-62328-5g

Conditionnement : 5g

Marque : Neo Biotech

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DL-Tyrosine

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Synonyms:

Catalog No. TN1596 Copy Product Info

Purity: 99.12%

DL-Tyrosine is a natural product.

Cas No. 556-03-6

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.12%

Appearance:solid

Color:White

Product Information

DL-Tyrosine AI Summary

DL-Tyrosine exhibits a range of bioactivities, demonstrating significant chemical versatility. It activates various human carbonic anhydrase (CA) isoenzymes such as CA1 and CA2 with high potency (KA values of 0.02 μM and 0.011 μM, respectively). Additionally, it shows variable activation potencies for other CAs, including CA7, CA14, and bacterial and fungal CAs. The compound’s biological activity extends to inhibiting mushroom tyrosinase, which indicates potential implications in melanin synthesis and skin pigmentation, with a Km value of 250,000 nM. Furthermore, DL-Tyrosine exhibits antiviral activity against SARS-CoV-2, demonstrating 30.42% inhibition of virus-induced cytotoxicity in Caco-2 cells at a 10 μM concentration. Its antibacterial and antifungal properties are evident against multiple pathogens, including Staphylococcus aureus and Candida albicans, as shown by inhibition zones in agar well diffusion assays. The compound also has antioxidant capabilities, scavenging various radicals in multiple assays. In acknowledgment of its pharmaceutical relevance, DL-Tyrosine inhibits key enzymes involved in metabolic pathways. It inhibits the full-length recombinant human CYP46A1, interfering with cholesterol hydroxylation at 43 μM with 80% activity. Additionally, it shows potent inhibition of L-tryptophan uptake in Xenopus laevis oocytes by up to 100%. Lastly, DL-Tyrosine interacts with human LAT1, exhibiting both inhibition and stimulation activities, and shows significant effects in various binding and inhibition assays, reinforcing its potential as a polyvalent bioactive molecule..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	DL-Tyrosine is a natural product.

Chemical Properties

Molecular Weight	181.19
Formula	C₉H₁₁NO₃
Cas No.	556-03-6
Smiles	NC(Cc1ccc(O)cc1)C(O)=O
Relative Density.	1.333 g/cm3

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: 1 mg/mL (insoluble or slightly soluble), Heating to 60℃ is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Keywords

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Related Tags: DL-Tyrosine chemical structure | DL-Tyrosine formula | DL-Tyrosine molecular weight