β-D-Glucan [9041-22-9]

Ordine minimo 2

Cat# T74140-10mg

Size : 10mg

Marca : TargetMol


β-D-Glucan

Copy Product Info
β-D-Glucan is a compound that targets tumor-associated macrophages with antitumor activity and modulates the immune response in necrotizing pancreatitis.
β-D-Glucan
Cas No. 9041-22-9
For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Solid
Color:White

Product Introduction

Bioactivity
Description
β-D-Glucan is a compound that targets tumor-associated macrophages with antitumor activity and modulates the immune response in necrotizing pancreatitis.
In vitro
Dissolving β-D-glucan in DMSO, but not in water, results in a concentration-dependent inhibition of MCF-7 cell proliferation, as determined by BrdU incorporation, with an IC50 of approximately 164 μg/mL. β-D-glucan, when dissolved in DMSO, inhibits the proliferation of tamoxifen/endocrine-resistant LCC9 and LY2 cells with IC50 values of 4.6 and 24.2 μg/mL, respectively.[3]
Chemical Properties
Molecular Weight504.438
FormulaC18H32O16
Cas No.9041-22-9
Smiles11[C@]1(CO)O[C@](11)(O)[C@](11)(O)[C@@](11)(O)C1O[C@]1(11)O[C@](11)(CO)C(O[C@]2(11)O[C@](11)(CO)[C@@](11)(O)[C@](11)(O)[C@@]2(11)O)[C@](11)(O)[C@@]1(11)O
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
NaOH: 10.00 mg/mL (19.82 mM), when pH is adjusted to 12 with 1 M NaOH. Sonication is recommended
Solution Preparation Table
NaOH
1mg5mg10mg50mg
1 mM1.9824 mL9.9120 mL19.8240 mL99.1202 mL
5 mM0.3965 mL1.9824 mL3.9648 mL19.8240 mL
10 mM0.1982 mL0.9912 mL1.9824 mL9.9120 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.