Reagenti e strumenti per immunologia, biologia cellulare e biologia molecolare
 
> Acridine Orange 10-nonyl bromide [75168-11-5]

Acridine Orange 10-nonyl bromide [75168-11-5]

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Cat# 440924-10mg

Size : 10mg

Marca : US Biological


440924 Acridine Orange 10-nonyl bromide

Grade
Highly Purified
Shipping Temp
RT
Storage Temp
-20°C

Acridine Orange 10-nonyl bromide is a metachromatic dye useful as a mitochondrial probe in living cells. It has been used to analyze mitochondria by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.

Synonyms:
3,6-bis(dimethylamino)-10-nonyl-acridinium, monobromide; 10-Nonylacridine orange bromide; 3,6-Bis(dimethylamino)-10-nonylacridinium bromide; 10-nonyl Acridine Orange; NAO

CAS No:
75168-11-5

Molecular Formula:
C26H38BrN3

Molecular Weight:
472.50

Appearance:
Orange to dark orange solid

Purity:
≥90% (HPLC)

Emission:
510nm

Excitation:
490nm

Solubility:
DMF, DMSO, Ethanol: Soluble; Chloroform (Slightly), Methanol (Slightly)

Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Applications
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Form
Orange to dark orange solid
Purity
≥90% (HPLC)
References
1. Petit, J.M., Maftah, A., Ratinaud, M.H., et al. 10N-nonyl acridine orange interacts with cardiolipin and allows the quantification of this phospholipid in isolated mitochondria. Eur. J. Biochem. 209(1), 267-273 (1992).|2. Jacobson, J., Duchen, M.R., and Heales, S.J. Intracellular distribution of the fluorescent dye nonyl acridine orange responds to the mitochondrial membrane potential: Implications for assays of cardiolipin and mitochondrial mass. J. Neurochem. 82(2), 224-233 (2002).