Anti-HSD17B1 antibody
Cat# MBS177074-0,1mg-DL550
Size : 0.1mg(Dylight550)
Marca : MyBiosource
Anti-HSD17B1 antibody, MBS177074, ICC
ICC: HELA Cell
ICC: HELA Cell
Anti-HSD17B1 antibody, MBS177074, Western blotting
Lane 1: Rat Kidney Tissue Lysate
Lane 2: Rat Liver Tissue Lysate
Lane 3: 293T Cell Lysate
Lane 4: HELA Cell Lysate
Lane 1: Rat Kidney Tissue Lysate
Lane 2: Rat Liver Tissue Lysate
Lane 3: 293T Cell Lysate
Lane 4: HELA Cell Lysate
Anti-HSD17B1 antibody, MBS177074, IHC(P)
IHC(P): Rat Liver Tissue
IHC(P): Rat Liver Tissue
Anti-HSD17B1 antibody, MBS177074, IHC(P)
IHC(P): Rat Ovary Tissue
IHC(P): Rat Ovary Tissue
Anti-HSD17B1 antibody, MBS177074, IHC(P)
IHC(P): Human Placenta Tissue
IHC(P): Human Placenta Tissue
HSD17B1 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS177074Description: Rabbit IgG polyclonal antibody for Estradiol 17-beta-dehydrogenase 1(HSD17B1) detection. Tested with WB, IHC-P, ICC in Human, Mouse, Rat.Background: HSD17B1(17-BETA-HYDROXYSTEROID DEHYDROGENASE I), also known as 17-beta-hydroxysteroid… More details
Product Overview
Online Datasheet in PDFProduct Name
HSD17B1, Polyclonal Antibody
Full Product Name
Anti-HSD17B1 antibody
Product Gene Name
anti-HSD17B1 antibody
Product Synonym Names
Estradiol 17-beta-dehydrogenase 1; hydroxysteroid(17-beta) dehydrogenase 1; 17 beta HSD 1 antibody; 17 beta hydroxysteroid dehydrogenase type 1 antibody; 17-beta-HSD 1 antibody; 17-beta-hydroxysteroid dehydrogenase type 1 antibody; 20 alpha-hydroxysteroid dehydrogenase antibody; 20-alpha-HSD antibody; DHB1_HUMAN antibody; E17KSR antibody; E2DH antibody; EDH17B1 antibody; EDH17B2 antibody; EDHB17 antibody; Estradiol 17 beta dehydrogenase 1 antibody; Estradiol 17-beta-dehydrogenase 1 antibody; HSD17 antibody; HSD17B1 antibody; Hydroxysteroid(17 beta) dehydrogenase 1 antibody; MGC13814 antibody; Placental 17 beta hydroxysteroid dehydrogenase antibody; Placental 17-beta-hydroxysteroid dehydrogenase antibody; SDR28C1 antibody; Short chain dehydrogenase/reductase family 28CE,member 1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Reacts with: Human, Rat
Predicted Species: Mouse
Predicted Species: Mouse
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Specificity
No Cross reactivity with other proteins.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
34,950 Da
OMIM
109684
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human HSD17B1 (29-43aa QSFKVYATLRDLKTQ), different from the related rat and mouse sequences by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-HSD17B1 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC)
Application Notes for anti-HSD17B1 antibody
Western Blot:
Concentration: 0.1-0.5ug/ml
Tested Species: Hu, Rat
Predicted Species: Ms
Immunohistochemistry (Paraffin-embedded Section):
Concentration: 0.5-1ug/ml
Tested Species: Hu, Rat
Predicted Species: Ms
Antigen Retrieval: By Heat
Immunocytochemistry:
Concentration: 0.5-1ug/ml
Tested Species: Hu
Predicted Species: Rat, Ms
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Concentration: 0.1-0.5ug/ml
Tested Species: Hu, Rat
Predicted Species: Ms
Immunohistochemistry (Paraffin-embedded Section):
Concentration: 0.5-1ug/ml
Tested Species: Hu, Rat
Predicted Species: Ms
Antigen Retrieval: By Heat
Immunocytochemistry:
Concentration: 0.5-1ug/ml
Tested Species: Hu
Predicted Species: Rat, Ms
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Other Notes
Small volumes of anti-HSD17B1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for HSD17B1 purchase
MBS177074 is an antibody targeting HSD17B1. Reactive in Reacts with: Human, Rat
Predicted Species: Mouse. Host: Rabbit.
Predicted Species: Mouse. Host: Rabbit.
Additional Details
NCBI/Uniprot data below describe general gene information for HSD17B1. It may not necessarily be applicable to this product.
NCBI Official Full Name
Estradiol 17-beta-dehydrogenase 1
NCBI Official Synonym Full Names
hydroxysteroid (17-beta) dehydrogenase 1
NCBI Official Symbol
HSD17B1
NCBI Official Synonym Symbols
HSD17; EDHB17; EDH17B2; SDR28C1
UniProt Protein Name
Estradiol 17-beta-dehydrogenase 1
UniProt Synonym Protein Names
17-beta-hydroxysteroid dehydrogenase type 1; 17-beta-HSD 1; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; E2DH; Placental 17-beta-hydroxysteroid dehydrogenase
Protein Family
Estradiol 17-beta-dehydrogenase
UniProt Gene Name
HSD17B1
UniProt Synonym Gene Names
E17KSR; EDH17B1; EDH17B2; EDHB17; 17-beta-HSD 1; 20-alpha-HSD
UniProt Entry Name
DHB1_HUMAN
NCBI Protein Information
estradiol 17-beta-dehydrogenase 1; E2DH; 20-alpha-HSD; 17-beta-HSD 1; estradiol 17-beta-dehydrogenase-1; 20 alpha-hydroxysteroid dehydrogenase; 17-beta-hydroxysteroid dehydrogenase type 1; placental 17-beta-hydroxysteroid dehydrogenase; hydroxysteroid (17-beta) dehydrogenase 1 isoform; short chain dehydrogenase/reductase family 28CE, member 1
UniProt Comments for HSD17B1
HSD17B1: Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein type: Lipid Metabolism - androgen and estrogen; EC 1.1.1.62; Oxidoreductase
Chromosomal Location of Human Ortholog: 17q11-q21
Cellular Component: nucleoplasm; nuclear membrane; cytoplasm; cytosol
Molecular Function: estradiol 17-beta-dehydrogenase activity; catalytic activity; 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
Biological Process: steroid metabolic process; estrogen metabolic process; steroid biosynthetic process; estrogen biosynthetic process
Show more Protein type: Lipid Metabolism - androgen and estrogen; EC 1.1.1.62; Oxidoreductase
Chromosomal Location of Human Ortholog: 17q11-q21
Cellular Component: nucleoplasm; nuclear membrane; cytoplasm; cytosol
Molecular Function: estradiol 17-beta-dehydrogenase activity; catalytic activity; 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
Biological Process: steroid metabolic process; estrogen metabolic process; steroid biosynthetic process; estrogen biosynthetic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-HSD17B1 antibody
| Reference Product | PubMed Publications |
|---|---|
| CYP19A1 antibody | >49 publications with HSD17B1 and CYP19A1 |
| CYP1A1 antibody | >19 publications with HSD17B1 and CYP1A1 |
| CYP1B1 antibody | >18 publications with HSD17B1 and CYP1B1 |
| SULT1E1 antibody | >4 publications with HSD17B1 and SULT1E1 |
| UGT2B15 antibody | >3 publications with HSD17B1 and UGT2B15 |
| CYP3A4 antibody | >3 publications with HSD17B1 and CYP3A4 |
| UGT2B17 antibody | >2 publications with HSD17B1 and UGT2B17 |
Pathways associated with anti-HSD17B1 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Disease Pathway antibodies | Disease Pathway Diagram |
| Diseases Associated With Visual Transduction Pathway antibodies | Diseases Associated With Visual Transduction Pathway Diagram |
| Estrogen Biosynthesis Pathway antibodies | Estrogen Biosynthesis Pathway Diagram |
| Metabolic Pathways antibodies | Metabolic Pathways Diagram |
| Metabolism Pathway antibodies | Metabolism Pathway Diagram |
| Metabolism Of Lipids And Lipoproteins Pathway antibodies | Metabolism Of Lipids And Lipoproteins Pathway Diagram |
| Metabolism Of Steroid Hormones And Vitamin D Pathway antibodies | Metabolism Of Steroid Hormones And Vitamin D Pathway Diagram |
| Ovarian Steroidogenesis Pathway antibodies | Ovarian Steroidogenesis Pathway Diagram |
| Ovarian Steroidogenesis Pathway antibodies | Ovarian Steroidogenesis Pathway Diagram |
| Prostate Cancer Pathway antibodies | Prostate Cancer Pathway Diagram |
Diseases associated with anti-HSD17B1 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Breast Neoplasms Antibodies | >35 publications with HSD17B1 and Breast Neoplasms |
| Endometriosis Antibodies | >16 publications with HSD17B1 and Endometriosis |
| Genital Diseases, Male Antibodies | >11 publications with HSD17B1 and Genital Diseases, Male |
| Adenocarcinoma Antibodies | >9 publications with HSD17B1 and Adenocarcinoma |
| Prostatic Diseases Antibodies | >7 publications with HSD17B1 and Prostatic Diseases |
| Prostatic Neoplasms Antibodies | >7 publications with HSD17B1 and Prostatic Neoplasms |
| Congenital Abnormalities Antibodies | >6 publications with HSD17B1 and Congenital Abnormalities |
| Urogenital Abnormalities Antibodies | >5 publications with HSD17B1 and Urogenital Abnormalities |
| Disorders of Sex Development Antibodies | >4 publications with HSD17B1 and Disorders of Sex Development |
| Ovarian Diseases Antibodies | >4 publications with HSD17B1 and Ovarian Diseases |
Organs/Tissues associated with anti-HSD17B1 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Placenta Antibodies | >15 publications with HSD17B1 and Placenta |
| Brain Antibodies | >7 publications with HSD17B1 and Brain |
| Uterus Antibodies | >5 publications with HSD17B1 and Uterus |
| Embryonic Tissue Antibodies | >5 publications with HSD17B1 and Embryonic Tissue |
| Testis Antibodies | >5 publications with HSD17B1 and Testis |
| Mammary Gland Antibodies | >4 publications with HSD17B1 and Mammary Gland |
| Stomach Antibodies | >3 publications with HSD17B1 and Stomach |
| Bone Antibodies | >2 publications with HSD17B1 and Bone |
| Intestine Antibodies | >1 publications with HSD17B1 and Intestine |
| Kidney Antibodies | >1 publications with HSD17B1 and Kidney |