Anti-IDH2 Antibody (3T725)
Cat# NB-64-117434-50uL
Size : 50uL
Marca : Neo Biotech
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Anti-IDH2 Antibody (3T725)
(Synonyms: Oxalosuccinate decarboxylase, NADP(+)-specific ICDH, mNADP-IDH, Isocitrate dehydrogenase 2 (NADP+), mitochondrial, Isocitrate dehydrogenase [NADP], mitochondrial, IDPM, IDP, IDHP_HUMAN, IDHM, IDH 2, IDH, ICD-M, D2HGA2) Copy Product InfoSynonyms: Oxalosuccinate decarboxylase, NADP(+)-specific ICDH, mNADP-IDH, Isocitrate dehydrogenase 2 (NADP+), mitochondrial, Isocitrate dehydrogenase [NADP], mitochondrial, IDPM, IDP, IDHP_HUMAN, IDHM, IDH 2, IDH, ICD-M, D2HGA2
Catalog No. TMAC-02085 Copy Product Info
Anti-IDH2 Antibody (3T725) is a Rabbit antibody targeting IDH2. Anti-IDH2 Antibody (3T725) can be used in FCM,IHC,WB.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-IDH2 Antibody (3T725) is a Rabbit antibody targeting IDH2. Anti-IDH2 Antibody (3T725) can be used in FCM,IHC,WB. |
| Synonyms | Oxalosuccinate decarboxylase, NADP(+)-specific ICDH, mNADP-IDH, Isocitrate dehydrogenase 2 (NADP+), mitochondrial, Isocitrate dehydrogenase [NADP], mitochondrial, IDPM, IDP, IDHP_HUMAN, IDHM, IDH 2, IDH, ICD-M, D2HGA2 |
| Ig Type | IgG |
| Clone | 3T725 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of IDH2 on different cell lysate using anti-IDH2 antibody at 1/1,000 dilution. Positive control: Line 1: Mouse heart, Line 2: Rat heart, Line 3: 293T. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-IDH2 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IDH2 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-IDH2 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded rat heart tissue using anti-IDH2 antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-IDH2 antibody. Counter stained with hematoxylin. 7. Flow cytometric analysis of MCF-7 cells with IDH2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).  , , , , , , |
| Application | FCM IHC WB |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial), also designated NADP+-specific ICDH; isocitrate dehydrogenase, mitochondrial; and oxalosuccinate decarboxylase, is a 452 amino acid enzyme encoded by the human gene IDH2. IDH2 belongs to the isocitrate and isopropylmalate dehydrogenases family and contains two nucleotide binding regions. IDH2 is involved in the reduction of NADP+ to NADPH and maintains the supply of glutathione (GSH) in mitochondria. It is believed to play a role in intermediary metabolism and energy production. IDH2 also tightly associates with the pyruvate dehydrogenase complex. IDH2 is found in the mitochondrion as a homodimer and can bind one magnesium or manganese ion per subunit. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID | P48735 |
| Molecular Weight | Theoretical: 45 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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