| Short Description : | Rabbit polyclonal anti-KCNA3 (200-250 aa) for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:1000 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation: | Lyophilised |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
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| Immunogen: | A synthetic peptide from aa region 200-250 of human KCNA3 conjugated to blue carrier protein was used as the antigen. The peptide shares 91% with rat and mouse sequence. |
| Immunogen Region: | 200-250 aa |
| Specificity: | Specific for KCNA3. |
| Function | Isoform 1: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Isoform 2: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Isoform 3: Lacks voltage-gated potassium channel activity. |
| Protein Name | Potassium Voltage-Gated Channel Subfamily A Member 3Hgk5Hlk3Hpcn3Voltage-Gated K(+ Channel HukiiiVoltage-Gated Potassium Channel Subunit Kv1.3 |
| Database Links | |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 2: Cell MembraneIsoform 3: CytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-Potassium Voltage-Gated Channel Subfamily A Member 3 antibodyAnti-Hgk5 antibodyAnti-Hlk3 antibodyAnti-Hpcn3 antibodyAnti-Voltage-Gated K(+ Channel Hukiii antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv1.3 antibodyAnti-KCNA3 antibodyAnti-HGK5 antibody |
Information sourced from Uniprot.org