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> Anti-Pentraxin 3 Antibody (1A740)

Anti-Pentraxin 3 Antibody (1A740)

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Cat# NB-64-124108-100uL

Size : 100uL

Marca : Neo Biotech


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Anti-Pentraxin 3 Antibody (1A740)

(Synonyms: TSG-14, TNFAIP5, PTX3, pentraxin 3) Copy Product Info

Synonyms: TSG-14, TNFAIP5, PTX3, pentraxin 3

Catalog No. TMAY-02230 Copy Product Info
Anti-Pentraxin 3 Antibody (1A740) is a Mouse antibody targeting Pentraxin 3. Anti-Pentraxin 3 Antibody (1A740) can be used in ELISA.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Description
Anti-Pentraxin 3 Antibody (1A740) is a Mouse antibody targeting Pentraxin 3. Anti-Pentraxin 3 Antibody (1A740) can be used in ELISA.
SynonymsTSG-14, TNFAIP5, PTX3, pentraxin 3
Ig Type
Mouse IgG1
Clone
1A740
Reactivity
Human
Specificity
Human Pentraxin 3/TSG-14
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis product is a recombinant monoclonal antibody expressed from HEK293 cells.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundPentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein that contains one pentaxin domain. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. Pentraxins are a family of evolutionarily conserved multifunctional pattern-recognition proteins characterized by a cyclic multimeric structure. Based on the primary structure of the subunit, the pentraxins are divided into two groups: short pentraxins and long pentraxins. C-reactive protein (CRP) and serum amyloid P-component (SAP) are the two short pentraxins. The prototype protein of the long pentraxin group is pentraxin 3 (PTX3). CRP and SAP are produced primarily in the liver in response to IL-6, while PTX3 is produced by a variety of tissues and cells and in particular by innate immunity cells in response to proinflammatory signals and Toll-like receptor (TLR) engagement. PTX3 is essential in female fertility by acting as a nodal point for the assembly of the cumulus oophorus hyaluronan-rich extracellular matrix. PTX3 interacts with several ligands, including growth factors, extracellular matrix components and selected pathogens, playing a role in complement activation and facilitating pathogen recognition by phagocytes, acting as a predecessor of antibodies. PTX3 may also contribute to the pathogenesis of atherosclerosis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human Pentraxin 3/PTX3 Protein (TMPY-01816)
Antigen Species
Human
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Keywords

TSG14TSG 14TNFAIP-5TNFAIP 5PTX-3PTX 3
Related Tags: Anti-Pentraxin 3 Antibody (1A740) chemical structure