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> Anti-THSD1 Antibody (5Y472)

Anti-THSD1 Antibody (5Y472)

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Cat# NB-64-125396-100uL

Size : 100uL

Marca : Neo Biotech


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Anti-THSD1 Antibody (5Y472)

(Synonyms: Tmtsp, thrombospondin type 1 domain containing 1, 4833423O18Rik) Copy Product Info

Synonyms: Tmtsp, thrombospondin type 1 domain containing 1, 4833423O18Rik

Catalog No. TMAY-03270 Copy Product Info
Anti-THSD1 Antibody (5Y472) is a Rabbit antibody targeting THSD1. Anti-THSD1 Antibody (5Y472) can be used in ELISA,ELISA(Cap).
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Description
Anti-THSD1 Antibody (5Y472) is a Rabbit antibody targeting THSD1. Anti-THSD1 Antibody (5Y472) can be used in ELISA,ELISA(Cap).
SynonymsTmtsp, thrombospondin type 1 domain containing 1, 4833423O18Rik
Ig Type
Rabbit IgG
Clone
5Y472
Reactivity
Mouse
Specificity
Mouse THSD1
Application
ELISA
ELISA(Cap)
Recommended Dose
ELISA: 1:5000-1:10000; ELISA(Cap): 1:250-1:2000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse THSD1 (rM THSD1; TMPY-01484; NP_062522.1; Met 1-Asn 412).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is a multi-domain, multi-functional glycoprotein synthesized by many cells. Matricellular THSD1 modulates cell adhesion and proliferation. It is involved in angiogenesis, inflammation, wound healing and cancer. In vitro, nanomolar concentrations of Thrombospondin-1 are required to alter endothelial and vascular smooth muscle cell adhesion, proliferation, motility, and survival. As a major platelet protein, for a long time it was postulated to control hemostasis via platelet aggregate stabilization. THSD1 is a potent angiogenesis inhibitor, and down-regulation of THSD1 has been suggested to alter tumor growth by modulating angiogenesis in a variety of tumor types.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Mouse THSD1 protein (TMPY-01484)
Antigen Species
Mouse
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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