AXL - human gene knockout kit via CRISPR, HDR mediated
AXL Human Gene Knockout Kit (CRISPR)
Other products for "AXL or NM_001278599"
cDNA Clones
Lentiviral
AAV
CRISPR
RNAi
Proteins
Antibodies
Specifications
Product Data
Format
2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector
mBFP-Neo
Target Symbol
AXL
Locus ID
558
Components
KN206431G1, AXL gRNA vector 1 in pCas-Guide CRISPR vector
KN206431G2, AXL gRNA vector 2 in pCas-Guide CRISPR vector
KN206431BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.
GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer
These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. provided by RefSeq, Jul 2013
AXL CRISPRa kit - CRISPR gene activation of human AXL receptor tyrosine kinase
1 kit
KN206431
AXL - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN206431LP
AXL - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN206431RB
AXL - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN406431
AXL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
1 kit
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
