Calmodulin Antagonist W-7 (Actomyosin Inhibitor) (N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride) [61714-27-0]

Cat# C1035-15-100mg

Size : 100mg

Marca : US Biological



C1035-15Calmodulin Antagonist W-7 (Actomyosin Inhibitor) (N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride)

Specifications
GradeMolecular Biology Grade
Shipping TempRT
Storage Temp-20°C

W7 is a vascular relaxing agent which affects vascular smooth muscle actomyosin. W7, a Protein Kinase Inhibitor, is an inhibitor of actomyosin superprecipitation, produces relaxation of isolated rabbit arterial strips and antagonizes the contraction of the strips induced by various contractile agonists. W7 is also a calmodulin antagonist that binds to calmodulin and inhibits Ca2+/calmodulin-regulated enzyme activities.

Synonyms:
N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride

CAS No:
61714-27-0

Molecular Weight:
377.4

Molecular Formula:
C16H21ClO2N2S•HCl

Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Applications
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. ||Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Purity
~90%
References
Hidaka, H., et al.: Proc. Nat. Acad. Sci. USA, 78, 4354 (1981)