CD40L / CD154 antibody [MR1] (FITC)
Cat. No. GTX01485-06
Cat. No. GTX01485-06
![Anti-CD40L / CD154 antibody [MR1] (FITC) used in Flow cytometry (FCM). GTX01485-06](/proxy_img/aHR0cDovL3d3dy5nZW5ldGV4LmNvbS91cGxvYWQvd2Vic2l0ZS9wcm91Y3RfaW1nL21pZGRsZS9HVFgwMTQ4NS0wNi9HVFgwMTQ4NS0wNl8yMDIwMDQyOF9GQUNTODJfd18yMzA1MzEyMV84OTcud2VicA==.webp)
GTX01485-06 FCM Image
FACS analysis of mouse C57Bl/6 T cells (enriched from total splenocytes, with PMA and Ionomycin stimulation for 6 hrs) using GTX01485-06 CD40L / CD154 antibody [MR1] (FITC).
Solid lone : primary antibody
Dashed line : isotype control
antibody amount : 0.25 μg (5 μl)
This CD40L / CD154 antibody [MR1] (FITC) (GTX01485-06) is a armenian hamster monoclonal antibody validated for detection of CD40L / CD154 by FCM. Reactive to mouse samples.
Summary
The MR1 antibody is specific for mouse CD154, a 39 kD glycoprotein that is primarily expressed on activated T cells. CD154 (CD40 ligand, gp39) binds to CD40 expressed on antigen presenting cells and mediates important costimulatory functions between these cells. Signals generated via cognate interactions between CD154-CD40 on activated T and B cells are required for T-dependent B cell responses.