Colistin sulfate [1264-72-8]
Cat# NB-64-03838-500mg
Size : 500mg
Marca : Neo Biotech
Colistin sulfate (Synonyms: Polymyxin E Sulfate, Polymixin E Sulfate, Colistin sulfate (1066-17-7 free base))
Catalog No. T1245 Copy Product Info
Purity: 99.80%
Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.
Colistin sulfate
Copy Product InfoSynonyms Polymyxin E Sulfate, Polymixin E Sulfate, Colistin sulfate (1066-17-7 free base)
Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.
Cas No. 1264-72-8
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2. |
| In vitro | In mice, daily intramuscular injections of Colistin sulfate (15 mg/kg) result in granular degeneration in renal and hepatic epithelial tissues. Similarly, in piglets, daily intramuscular injections of Colistin sulfate (15 mg/kg) lead to significant neurotoxic effects. |
| In vivo | Colistin (2 μg/mL) exhibits broad-spectrum antibacterial activity, effectively inhibiting most strains of Escherichia coli and Pseudomonas aeruginosa, as well as all strains of the genera Enterobacter, Salmonella, Shigella, Pasteurella, Brucella, and Bordetella. Additionally, it is active against strains of the genera Moraxella, Serratia, and Providencia. In 225 strains of P. aeruginosa, the MIC90 and MIC50 of Colistin are 6.3 μg/mL and 1.6 μg/mL, respectively. In Acinetobacter baumannii, Colistin sulfate demonstrates concentration-dependent post-antibiotic effects. |
| Synonyms | Polymyxin E Sulfate, Polymixin E Sulfate, Colistin sulfate (1066-17-7 free base) |
| Cas No. | 1264-72-8 |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: 125.00 mg/mL, Sonication is recommended.  DMSO: Insoluble |
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