E2F4 (Transcription Factor E2F4, E2F-4)

Cat# 029459-100ug

Size : 100ug

Marca : US Biological

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Telefono : +1 850 650 7790


029459 Rabbit Anti-E2F4 (Transcription Factor E2F4, E2F-4)

Clone Type
Polyclonal
Host
mouse
Source
human
Swiss Prot
Q16254
Isotype
IgG1,k
Grade
Affinity Purified
Applications
IHC WB
Crossreactivity
Hu
Accession #
NP_001941
Shipping Temp
Blue Ice
Storage Temp
-20°C

E2F4 is the most common E2F family member in a number of cell types. E2F4 deficiency has been shown to cause a decrease in the thickness of the gut epithelium, decrease in maturation of hematopoietic cell types and an increased rate of apoptosis, suggesting that E2F4 plays a role in normal maturation of several cell types. E2F4 has also been shown to be essential for the normal development of airway epithelium and early eye development. Other data has implicated E2F4 during normal heart development, specifically cardiomyocyte proliferation.||Applications:|Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.||Recommended Dilution:|Western Blot: 0.5ug/ml|Optimal dilutions to be determined by the researcher.||Positive Control: |HeLa lyate cells||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Mab|Isotype: IgG1,k|Clone No: LLF4-2|Host: mouse|Source: human|Concentration: ~0.5mg/ml|Form: Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.|Purity: Purified by Protein G affinity chromatography.|Immunogen: Recombinant corresponding to human E2F4 fused to His-tag.|Specificity: Recognizes human E2F4.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Recombinant corresponding to human E2F4 fused to His-tag.
Form
Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes human E2F4.
References
1. Van Amerongen, M.J., et al. (2010). Cardiovasc Res. 86(1):92-102. 2. Ruzhynsky, V.A., et al. (2009). Dev Neurosci. 31(3):238-246. 3. Danielian, P.S., et al. (2007). Dev Biol. 305(2): 564-576. 4. Kinross, K., et al. (2006). Blood. 108(3):886-895. 5. Rempel, R.E., et al. (2000). Mol Cell. 6(2):293-306.