EDNRA Human Recombinant Protein, Synthetic Nanodisc
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SKU
TP728693M
Recombinant Human EDNRA full length protein-Synthetic Nanodisc, 100 ug
Specifications
Product Data
Species
Human
Expression Host
HEK293
Tag
C-Flag & Strep Tag
Predicted MW
48.7 kDa
Concentration
Please refer to the Certificate of Analysis (COA) for the lot-specific concentration before lyophilization.
Buffer
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Reconstitution Method
1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Storage
Store at -20°C to -80°C for 12 months in lyophilized form.
Stability
After reconstitution, if not intended for use within a month, aliquot and store at -80°C . Avoid repeated freezing and thawing.
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2009
Protein Categories
GPCR, Membrane Proteins
Protein Families
Druggable Genome, GPCR, Transmembrane
Protein Pathways
Angiogenesis, Cancer, Endothelial Cell Biology, GPCRDB Class A Rhodopsin-like, GPCRDB Other, Peptide GPCRs, Prostaglandin synthesis regulation
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
