B7195-1g | EGTA [67-42-5] Clinisciences

EGTA, also known as egtazic acid, is an aminopolycarboxylic acid, a calcium chelator. It can protects against cell death caused by nitric oxide-induced calcium influx into nerve cells[1,2].

References:

[1]. Boullerne A I, Nedelkoska L, Benjamins J A. Role of calcium in nitric oxide-induced cytotoxicity: EGTA protects mouse oligodendrocytes. Journal of Neuroscience Research, 2001, 63(2): 124-135.

[2]. Fisher A E O, Hague T A, Clarke C L, et al. Catalytic superoxide scavenging by metal complexes of the calcium chelator EGTA and contrast agent EHPG. Biochemical and Biophysical Research Communications, 2004, 323(1): 0-167.

1. Yu Q, Wang D, et al. "Adipose-derived Exosomes Protect the Pulmonary Endothelial Barrier in Ventilator-induced Lung Injury by Inhibiting the TRPV4/Ca2+ Signaling Pathway." Am J Physiol Lung Cell Mol Physiol. 2020;10.1152/ajplung.00255.2019. PMID:32073873

Physical Appearance	A solid
Storage	Store at RT
M.Wt	380.35
Cas No.	67-42-5
Formula	C₁₄H₂₄N₂O₁₀
Solubility	insoluble in H2O; insoluble in DMSO; insoluble in EtOH
Chemical Name	3,12-bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioic acid
SDF	Download SDF
Canonical SMILES	OC(CN(CC(O)=O)CCOCCOCCN(CC(O)=O)CC(O)=O)=O
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Purity = 98.00%

Chemical structure

EGTA [67-42-5]

Cat# B7195-1g

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Marca : ApexBio Technology

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