GNRH1, 24-92aa, Human, His tag, E Coli
Cat# MBS205551-0,1mg
Size : 0.1mg
Marca : MyBiosource
GNRH1 Recombinant Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205551GNRH1 is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). GNRH1 stimulates the release of luteinizing… More details
Product Overview
Online Datasheet in PDFProduct Name
GNRH1, Recombinant Protein
Full Product Name
GNRH1, 24-92aa, Human, His tag, E Coli
Product Gene Name
GNRH1 recombinant protein
Product Synonym Names
Progonadoliberin-1 isoform 2 preproprotein; Gonadotropin-releasing hormone 1; GNRH; GRH; HH12; LHRH; LNRH
Sequence
MGSSHHHHHH SSGLVPRGSH MGSQHWSYGL RPGGKRDAEN LIDSFQEIVK EVGQLAETQR FECTTHQPRS PLRDLKGALE SLIEEETGQK KI
Host
E Coli
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Purity/Purification
> 90% by SDS-PAGE
Concentration
0.5 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Applications Tested/Suitable for GNRH1 recombinant protein
SDS-PAGE
Product References and Citations for GNRH1 recombinant protein
Hayflick J.S., Adelman J.P., et al. (1989) Nucleic Acids Res. 17:6403-6403
Other Notes
Small volumes of GNRH1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for GNRH1 purchase
MBS205551 is a recombinant protein targeting GNRH1. Also known as GNRH1, 24-92aa, Human, His tag, E Coli. Host: E Coli.
Additional Details
NCBI/Uniprot data below describe general gene information for GNRH1. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
progonadoliberin-1 isoform 2 preproprotein
NCBI Official Synonym Full Names
gonadotropin releasing hormone 1
NCBI Official Symbol
GNRH1
NCBI Official Synonym Symbols
GRH; GNRH; LHRH; LNRH
UniProt Protein Name
Progonadoliberin-1
UniProt Synonym Protein Names
Progonadoliberin I
Protein Family
Progonadoliberin
UniProt Gene Name
GNRH1
UniProt Synonym Gene Names
GNRH; GRH; LHRH; GnRH-I; LH-RH I
NCBI Protein Information
progonadoliberin-1
NCBI Summary for GNRH1
This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015]
Show more UniProt Comments for GNRH1
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.MiscellaneousThe 3D-structure was determined for the synthetic analog Triptorelin.
Research Articles on GNRH1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with GNRH1 recombinant protein
| Reference Product | PubMed Publications |
|---|---|
| GNRH2 recombinant protein | >84 publications with GNRH1 and GNRH2 |
| KISS1 recombinant protein | >57 publications with GNRH1 and KISS1 |
| GNRHR recombinant protein | >43 publications with GNRH1 and GNRHR |
| KISS1R recombinant protein | >26 publications with GNRH1 and KISS1R |
| TAC3 recombinant protein | >19 publications with GNRH1 and TAC3 |
| GNRHR2 recombinant protein | >4 publications with GNRH1 and GNRHR2 |
| TRH recombinant protein | >1 publications with GNRH1 and TRH |
Pathways associated with GNRH1 recombinant protein
| Products by Pathway | Pathway Diagram |
|---|---|
| Class A/1 (Rhodopsin-like Receptors) Pathway antibodies | Class A/1 (Rhodopsin-like Receptors) Pathway Diagram |
| G Alpha (q) Signalling Events Pathway antibodies | G Alpha (q) Signalling Events Pathway Diagram |
| GPCR Downstream Signaling Pathway antibodies | GPCR Downstream Signaling Pathway Diagram |
| GPCR Ligand Binding Pathway antibodies | GPCR Ligand Binding Pathway Diagram |
| Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies | Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram |
| GnRH Signaling Pathway antibodies | GnRH Signaling Pathway Diagram |
| GnRH Signaling Pathway antibodies | GnRH Signaling Pathway Diagram |
| Hormone Ligand-binding Receptors Pathway antibodies | Hormone Ligand-binding Receptors Pathway Diagram |
| Nongenotropic Androgen Signaling Pathway antibodies | Nongenotropic Androgen Signaling Pathway Diagram |
| Signal Transduction Pathway antibodies | Signal Transduction Pathway Diagram |
Diseases associated with GNRH1 recombinant protein
| Disease Name | Pubmed Publications |
|---|---|
| Hypogonadism Antibodies | >41 publications with GNRH1 and Hypogonadism |
| Idiopathic Hypogonadotropic Hypogonadism Antibodies | >15 publications with GNRH1 and Idiopathic Hypogonadotropic Hypogonadism |
| Disorders of Sex Development Antibodies | >14 publications with GNRH1 and Disorders of Sex Development |
| Nervous System Diseases Antibodies | >8 publications with GNRH1 and Nervous System Diseases |
| Infertility, Female Antibodies | >6 publications with GNRH1 and Infertility, Female |
| Ovarian Diseases Antibodies | >6 publications with GNRH1 and Ovarian Diseases |
| Infertility, Male Antibodies | >5 publications with GNRH1 and Infertility, Male |
| Cryptorchidism Antibodies | >5 publications with GNRH1 and Cryptorchidism |
| Breast Neoplasms Antibodies | >4 publications with GNRH1 and Breast Neoplasms |
| Diabetes Mellitus Antibodies | >4 publications with GNRH1 and Diabetes Mellitus |
Organs/Tissues associated with GNRH1 recombinant protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >149 publications with GNRH1 and Brain |
| Blood Antibodies | >57 publications with GNRH1 and Blood |
| Testis Antibodies | >20 publications with GNRH1 and Testis |
| Prostate Antibodies | >6 publications with GNRH1 and Prostate |
| Uterus Antibodies | >4 publications with GNRH1 and Uterus |
| Placenta Antibodies | >2 publications with GNRH1 and Placenta |
| Intestine Antibodies | >2 publications with GNRH1 and Intestine |
| Embryonic Tissue Antibodies | >2 publications with GNRH1 and Embryonic Tissue |
| Eye Antibodies | >2 publications with GNRH1 and Eye |
| Muscle Antibodies | >2 publications with GNRH1 and Muscle |