GP9 Antibody
Cat# OAEE00861
Size : 100tests(T100)
Marca : Aviva Systems Biology
| Datasheets/Manuals | Printable datasheet for GP9 Antibody |
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| Predicted Species Reactivity | Dog|Human |
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| Product Format | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Clonality | Monoclonal |
| Clone | GR-P |
| Isotype | IgG1 |
| Host | Mouse |
| Conjugation | FITC |
| Application | FC |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | Human acute lymphoblastic leukemia cells |
| Purification | Purified by size-exclusion chromatography |
| Concentration | 4 ul / test |
| Specificity | The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets. HLDA IV.; WS Code P 35 |
| Formulation | FITC |
| Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent. |
| Reference | Din JN, Aftab SM, Jubb AW, Carnegy FH, Lyall K, Sarma J, Newby DE, Flapan AD: Effect of moderate walnut consumption on lipid profile, arterial stiffness and platelet activation in humans. Eur J Clin Nutr. 2011 Feb;65(2):234-9. Vettore S, Scandellari R, Moro S, Lombardi AM, Scapin M, Randi ML, Fabris F: Novel point mutation in a leucine-rich repeat of the GPIbalpha chain of the platelet von Willebrand factor receptor, GPIb/IX/V, resulting in an inherited dominant form of Bernard-Soulier syndrome affecting two unrelated families: the N41H variant. Haematologica. 2008 Nov;93(11):1743-7. Brown SB, Clarke MC, Magowan L, Sanderson H, Savill J: Constitutive death of platelets leading to scavenger receptor-mediated phagocytosis. A caspase-independent cell clearance program. J Biol Chem. 2000 Feb 25;275(8):5987-96. Harding SA, Din JN, Sarma J, Josephs DH, Fox KA, Newby DE: Promotion of proinflammatory interactions between platelets and monocytes by unfractionated heparin. Heart. 2006 Nov;92(11):1635-8. Leukocyte Typing IV., Knapp W. et al. (Eds.), Oxford University Press (1989) |
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| Gene Symbol | GP9 |
| Gene Full Name | glycoprotein IX platelet |
| Alias Symbols | CD42a, glycoprotein 9, GPIX, platelet glycoprotein IX. |
| NCBI Gene Id | 2815 |
| Protein Name | Platelet glycoprotein IX |
| Description of Target | The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. |
| Uniprot ID | P14770 |
| Protein Accession # | NP_000165.1; XP_005247431.1 |
| Nucleotide Accession # | NM_000174.4; XM_005247374.3 |
