Herboxidiene [142861-00-5]
Cat# T36749-1mg
Size : 1mg
Marca : TargetMol
Herboxidiene
(Synonyms: GEX1A) Copy Product InfoHerboxidiene (GEX1A) is a plant-toxic polyketide compound isolated from Streptomyces ATCC 49982, with herbicidal, cholesterol-lowering, and anticancer activities. It exhibits anti-angiogenic activity by downregulating vascular endothelial growth factor receptor-2 (VEGFR-2) and hypoxia-inducible factor-1α (HIF-1α).
Cas No. 142861-00-5
For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Solid
Color:White
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Herboxidiene (GEX1A) is a plant-toxic polyketide compound isolated from Streptomyces ATCC 49982, with herbicidal, cholesterol-lowering, and anticancer activities. It exhibits anti-angiogenic activity by downregulating vascular endothelial growth factor receptor-2 (VEGFR-2) and hypoxia-inducible factor-1α (HIF-1α). |
| In vivo | Methods: Herboxidiene (1 mg/kg, intraperitoneal injection) was administered to mice bearing SVT2 mouse fibrosarcoma model, and the changes of tumors in vivo were observed. Results: Herboxidiene showed significant antitumor activity on day 4.[1] |
| Synonyms | GEX1A |
| Molecular Weight | 438.6 |
| Formula | C25H42O6 |
| Cas No. | 142861-00-5 |
| Smiles | [C@H]([C@H]([C@@H](C)O)OC)(C)[C@@]1([C@](C[C@@H](/C=C/C=C(\C)/[C@H]2O[C@@H](CC(O)=O)CC[C@@H]2C)C)(C)O1)23 |
| Relative Density. | 1.056 g/cm3 (Predicted) |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol: 1 mg/mL (2.28 mM), Sonication is recommended. Dichloromethane: 1 mg/mL (2.28 mM), Sonication is recommended. DMSO: 1 mg/mL (2.28 mM), Sonication is recommended. Methanol: 1 mg/mL (2.28 mM), Sonication is recommended. |
Solution Preparation Table | |
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |