Human mtTFA (TFAM) activation kit by CRISPRa
CAT#: GA104828
TFAM CRISPRa kit - CRISPR gene activation of human transcription factor A, mitochondrial
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Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
| Symbol | TFAM |
| Locus ID | 7019 |
| Kit Components | GA104828G1, mtTFA gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104828G2, mtTFA gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104828G3, mtTFA gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001270782, NM_003201, NM_012251, NR_073073 |
| UniProt ID | Q00059 |
| Synonyms | MTTF1; MTTFA; TCF6; TCF6L1; TCF6L2; TCF6L3 |
| Summary | This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
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Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| KN215488 | TFAM - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN215488BN | TFAM - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN215488LP | TFAM - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN215488RB | TFAM - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN415488 | TFAM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 657,00 EUR |