Integrin alpha5, beta1 (VLA5, Fibronectin Receptor, Very Late Antigen, CD49)

Cat# MBS602574-5x0,1mL

Size : 5x0.1mL

Marca : MyBiosource


Integrin Alpha5, Beta1 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS602574

The alpha 5 beta 1 integrin mediates cell adhesion and migration on fibronectin, a glycoprotein critical for normal vertebrate embryonic development. Indirect evidence reported to date suggests that this receptor also functions in the deposition of… More details

Product Overview

Online Datasheet in PDF
Product Name
Integrin alpha5, beta1, Monoclonal Antibody
Full Product Name
Integrin alpha5, beta1 (VLA5, Fibronectin Receptor, Very Late Antigen, CD49)
Product Synonym Names
Anti -Integrin alpha5, beta1 (VLA5, Fibronectin Receptor, Very Late Antigen, CD49)
Clonality
Monoclonal
Isotype
IgG3
Clone Number
2Q963
Host
Rat
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.4, containing no preservatives
Purity/Purification
Ascites
Ascites
Specificity
Recognizes mouse integrin VLA-5 (a5b1), a fibronectin receptor.
Preparation and Storage
Maintain frozen at-20 degree C in undiluted aliquots for up to 12 months.
Immunogen
The antibody was prepared by fusion of spleen cells from a Fisher rat immunized with mouse embryonal carcinoma P19 cells with myeloma P3X63Ag9.653 cells

Product Categories/Family for anti-Integrin alpha5, beta1 antibody

Antibodies; Abs to Integrin
Applications Tested/Suitable for anti-Integrin alpha5, beta1 antibody
Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes for anti-Integrin alpha5, beta1 antibody
Inhibition of cell adhesion to fibronectin: 10mg/ml Note that where cell adhesion to fibronectin involving other fibronectin receptors, such as VLA-4 (a4b1) integrin, is involved, inhibition of cell adhesion by BMB5 alone may not be complete., Immunoprecipitation from lysate of 10e6 cell equivalent: 2mg, Flow cytometry: 10mg/ml Western blot (non-reducing gel)

Other Notes

Small volumes of anti-Integrin alpha5, beta1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Integrin alpha5, beta1 purchase

MBS602574 is an antibody targeting Integrin alpha5, beta1. Also known as Integrin alpha5, beta1 (VLA5, Fibronectin Receptor, Very Late Antigen, CD49). Reactive in Mouse. Host: Rat.