A8656-50mg | Jervine [469-59-0] Clinisciences

Background

Inhibitor of Hedgehog signaling (IC50 = 500 - 700 nM); binds directly to Smoothened (Smo). Inhibits the response of target tissues to Sonic hedgehog signaling, possibly via the sterol sensing domain of Patched. Teratogenic.

Chemical Properties

Physical Appearance	White solid
Storage	Store at -20°C
M.Wt	425.6
Cas No.	469-59-0
Formula	C₂₇H₃₉NO₃
Solubility	Limited solubility, soluble in DMSO or ethanol
Chemical Name	(3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,6,6a,6b,7,8,11a-decahydrobenzoamfluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-11-one
SDF	Download SDF
Canonical SMILES	CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Purity = 98.00%

COA (Certificate Of Analysis)
MSDS (Material Safety Data Sheet)
Datasheet

Chemical structure

Jervine [469-59-0]

Cat# A8656-50mg

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Marca : ApexBio Technology

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Background

Chemical Properties

Quality Control

Chemical structure