Monoclonal Mouse anti-Human IL6R / IL6 Receptor Antibody (clone 3H7D3H1, Preservative Free)

Cat# LS-C814667-200

Size : 200ug

Marca : LSBio


Overview

Antibody:
IL6R / IL6 Receptor Mouse anti-Human Monoclonal (Preservative Free) (3H7D3H1) Antibody
Application:
Block, Neut
Reactivity:
Human
Format:
Unconjugated, Preservative Free

Specifications

Description
IL6 Receptor antibody LS-C814667 is an unconjugated mouse monoclonal antibody to human IL6 Receptor (IL6R). Validated for Block and Neut.
Target
Human IL6R / IL6 Receptor
Synonyms
IL6R | CD126 | gp80 | IL-6R subunit alpha | IL-6R-alpha | IL-6RA | IL6Q | IL-6 receptor subunit alpha | IL-6R 1 | IL-6R-1 | Interleukin 6 receptor | Membrane glycoprotein 80 | CD126 antigen | IL6RA | IL6RQ
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
3H7D3H1
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Preservative Free
Immunogen
Recombinant Human IL-6R / CD126 protein
Specificity
Human IL-6R. No cross-reactivity with rat IL6R , mouse IL6R, or dog IL6R in ELISA assay
Applications
  • Blocking
  • Neutralization
Usage
Block: This IL6R Neutralizing Antibody can not block the binding of recombinant IL6 to its recombinant receptor IL6 Ra. Neutralization: The neutralization activity of IL6R Neutralizing Antibody is measured by its ability to neutralize IL6 Ra-mediated inhibition of proliferation in the M1 mouse myeloid leukemia cell line. The Neutralization Titer (IC50) is typically 0.15-0.6 µg/ml in the presence of 50 ng/mL Recombinant Human IL6 Ra and 100 ng/mL Recombinant Human IL6. Please Note: Optimal concentrations/dilutions should be determined by the end user.
Presentation
0.2 µm filtered solution in PBS
Storage
Store at 2°C to 8°C for up to 1 month. Aliquot and store at -20°C to -80°C for up to 1 year. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About IL6R / IL6 Receptor
P08887 NM_000565 NP_000556.1


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tech@clinisciences.com