Nicastrin Polyclonal Antibody, AbBy Fluor® 647 Conjugated
Cat# bs-6058R-BF647
Size : 100ul
Marca : Bioss
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Telefono : +1 850 650 7790
Nicastrin Polyclonal Antibody, AbBy Fluor® 647 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-6058R-BF647 |
| Product Name | Nicastrin Polyclonal Antibody, AbBy Fluor® 647 Conjugated |
| Applications | WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Reactivity | Mouse |
| Predicted Reactivity | Human, Rat, Cow, Pig, Horse, Chicken |
| Specifications | |
| Conjugation | AbBy Fluor® 647 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Nicastrin |
| Immunogen Range | 21-120/709 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 23385 |
| Swiss Prot | Q92542 |
| Subcellular location | Cell membrane |
| Synonyms | ATAG1874; Nicastrin; NCSTN; KIAA0253; UNQ1874/PRO4317 |
| Background | Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |