OVCA1 Polyclonal Antibody, APC-Cy7 Conjugated
Cat# bs-5714R-APC-Cy7
Size : 100ul
Marca : Bioss
OVCA1 Polyclonal Antibody, APC-Cy7 Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-5714R-APC-Cy7 |
Product Name | OVCA1 Polyclonal Antibody, APC-Cy7 Conjugated |
Applications | WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Reactivity | Human |
Predicted Reactivity | Mouse, Rat, Dog, Cow, Horse, Rabbit |
Specifications | |
Conjugation | APC-Cy7 |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human OVCA1 |
Immunogen Range | 251-350/443 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 1801 |
Synonyms | Candidate tumor suppressor in ovarian cancer 1; Diphthamide biosynthesis protein 1; Diphthamide biosynthesis protein 2 homolog like 1; Diphthamide biosynthesis protein 2 like; Diptheria toxin resistance protein required for diphthamide biosynthesis Saccharomyces like 1 ; Diptheria toxin resistance protein required for diphthamide biosynthesis like 1; DPH like 1 S. cerevisiae; DPH like 1; DPH1; DPH1 homolog S. cerevisiae; DPH1 homolog; DPH2 like 1; DPH2L; DPH2L1; HsDph1; Ovarian cancer associated gene 1; Ovarian cancer associated gene 1 protein; Ovarian tumor suppressor candidate 1; DPH1_HUMAN. |
Background | OVCA1 is required for the first step in the synthesis of diphthamide, a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. OVCA1 is one of several enzymes involved in synthesis of diphthamide in EEF2. |
Application Dilution | |
WB | 1:300-5000 |
IF(IHC-P) | 1:50-200 |
IF(IHC-F) | 1:50-200 |
IF(ICC) | 1:50-200 |