Rat Visual system homeobox 2 (VSX2) ELISA Kit
Cat# MBS7241403-48
Size : 48-Strip-Wells
Marca : MyBiosource
Visual System Homeobox 2 (VSX2) ELISA Kit for Rat
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7241403MBS7241403 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Visual system homeobox 2 (VSX2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details
Product Overview
Online Datasheet in PDFProduct Name
Visual system homeobox 2 (VSX2), ELISA Kit
Full Product Name
Rat Visual system homeobox 2 (VSX2) ELISA Kit
Product Gene Name
VSX2 elisa kit
Species Reactivity
Rat
Assay Type
Competitive
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Detection Range
0.5-10ng/mL
Sensitivity
0.1ng/ml
Preparation and Storage
Store all reagents at 2-8 degree C.
Molecular Weight
39,411 Da
OMIM
610093
Sample Preparation
We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
Product Categories/Family for VSX2 elisa kit
Epigenetics and Nuclear Signaling
ISO Certification
Manufactured in an ISO 13485:2016 Certified Laboratory.
Other Notes
Small volumes of VSX2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for VSX2. It may not necessarily be applicable to this product.
NCBI Official Full Name
visual system homeobox 2
NCBI Official Synonym Full Names
visual system homeobox 2
NCBI Official Symbol
VSX2
NCBI Official Synonym Symbols
RET1; CHX10; HOX10; MCOP2; MCOPCB3
UniProt Protein Name
Visual system homeobox 2
UniProt Synonym Protein Names
Ceh-10 homeodomain-containing homolog; Homeobox protein CHX10
Protein Family
Visual system homeobox
UniProt Gene Name
VSX2
UniProt Synonym Gene Names
CHX10; HOX10
UniProt Entry Name
VSX2_HUMAN
NCBI Protein Information
visual system homeobox 2; homeobox protein CHX10; ceh-10 homeodomain-containing homolog; ceh-10 homeo domain containing homolog
NCBI Summary for VSX2
This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities. [provided by RefSeq, Oct 2009]
UniProt Comments for VSX2
CHX10: Plays a significant role in the specification and morphogenesis of the sensory retina. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells. Defects in VSX2 are the cause of microphthalmia isolated type 2 (MCOP2); also known as isolated clinical anophthalmia. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataractand other abnormalities like cataract may also be present. Defects in VSX2 are the cause of microphthalmia with cataracts and iris abnormalities (MCOPCTI). Defects in VSX2 are the cause of microphthalmia isolated with coloboma type 3 (MCOPCB3); also known as isolated colobomatous microphthalmia 3. Ocular colobomas are a set of malformations resulting from abnormal morphogenesis of the optic cup and stalk, and the fusion of the fetal fissure (optic fissure). Belongs to the paired homeobox family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 14q24.3
Cellular Component: cytoplasm; nucleus
Molecular Function: sequence-specific DNA binding
Biological Process: negative regulation of cell proliferation; cell fate commitment; transcription, DNA-dependent; visual perception; positive regulation of cell proliferation; response to stimulus; positive regulation of transcription from RNA polymerase II promoter; retinal bipolar neuron differentiation
Disease: Microphthalmia, Isolated 2; Microphthalmia, Isolated, With Coloboma 3
Show more Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 14q24.3
Cellular Component: cytoplasm; nucleus
Molecular Function: sequence-specific DNA binding
Biological Process: negative regulation of cell proliferation; cell fate commitment; transcription, DNA-dependent; visual perception; positive regulation of cell proliferation; response to stimulus; positive regulation of transcription from RNA polymerase II promoter; retinal bipolar neuron differentiation
Disease: Microphthalmia, Isolated 2; Microphthalmia, Isolated, With Coloboma 3
Research Articles on VSX2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with VSX2 elisa kit
| Reference Product | PubMed Publications |
|---|---|
| PAX6 elisa kit | >24 publications with VSX2 and PAX6 |
| NES elisa kit | >6 publications with VSX2 and NES |
| NEUROD4 elisa kit | >3 publications with VSX2 and NEUROD4 |
| SIX3 elisa kit | >3 publications with VSX2 and SIX3 |
| POU4F2 elisa kit | >3 publications with VSX2 and POU4F2 |
| CDKN1B elisa kit | >3 publications with VSX2 and CDKN1B |
| GDF3 elisa kit | >1 publications with VSX2 and GDF3 |
| MFRP elisa kit | >1 publications with VSX2 and MFRP |
| NXNL1 elisa kit | >1 publications with VSX2 and NXNL1 |
Diseases associated with VSX2 elisa kit
| Disease Name | Pubmed Publications |
|---|---|
| Embryo Loss Antibodies | >8 publications with VSX2 and Embryo Loss |
| Disease Models, Animal Antibodies | >6 publications with VSX2 and Disease Models, Animal |
| Microphthalmia, Isolated 2 Antibodies | >4 publications with VSX2 and Microphthalmia, Isolated 2 |
| Premature Birth Antibodies | >1 publications with VSX2 and Premature Birth |
| Uterine Diseases Antibodies | >1 publications with VSX2 and Uterine Diseases |
| Atrophy Antibodies | >1 publications with VSX2 and Atrophy |
| Uterine Neoplasms Antibodies | >1 publications with VSX2 and Uterine Neoplasms |
| Weight Loss Antibodies | >1 publications with VSX2 and Weight Loss |
Organs/Tissues associated with VSX2 elisa kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Eye Antibodies | >89 publications with VSX2 and Eye |
| Brain Antibodies | >10 publications with VSX2 and Brain |
| Muscle Antibodies | >3 publications with VSX2 and Muscle |