Reagenti e strumenti per immunologia, biologia cellulare e biologia molecolare

S-Adenosyl-L-methionine [29908-03-0]

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Cat# NB-64-41667-1mg

Size : 1mg

Marca : Neo Biotech

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S-Adenosyl-L-methionine

(Synonyms: SAMe, S-Adenosyl methionine, AdoMet, Ademetionine) Copy Product Info

Synonyms: SAMe, S-Adenosyl methionine, AdoMet, Ademetionine

Catalog No. T7475 Copy Product Info

Purity: 99.08%

S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.

Cas No. 29908-03-0

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.08%

Appearance:Solid

Color:White

Product Introduction

Bioactivity

Description	S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.
Synonyms	SAMe, S-Adenosyl methionine, AdoMet, Ademetionine

Chemical Properties

Molecular Weight	398.44
Formula	C₁₅H₂₂N₆O₅S
Cas No.	29908-03-0
Smiles	C[S+](CC[C@H](N)C([O-])=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Relative Density.	no data available

Storage & Solubility Information

Storage

Store under nitrogen,Store at low temperature,Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 43 mg/mL (107.92 mM), Sonication is recommended.

DMSO: 100 mg/mL (250.98 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5098 mL	12.5489 mL	25.0979 mL	125.4894 mL
5 mM	0.5020 mL	2.5098 mL	5.0196 mL	25.0979 mL
10 mM	0.2510 mL	1.2549 mL	2.5098 mL	12.5489 mL
20 mM	0.1255 mL	0.6274 mL	1.2549 mL	6.2745 mL
50 mM	0.0502 mL	0.2510 mL	0.5020 mL	2.5098 mL
100 mM	0.0251 mL	0.1255 mL	0.2510 mL	1.2549 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

supplementS-Adenosyl-L-methionineSAdenosylLmethionineS Adenosyl L methionineosteoarthritismethylmethionineliverInhibitorinhibitEndogenousMetaboliteEndogenous MetabolitedietaryATPantidepressantanalgesicadenosyltransferase

Related Tags: S-Adenosyl-L-methionine chemical structure | S-Adenosyl-L-methionine formula | S-Adenosyl-L-methionine molecular weight