S-Adenosyl-L-methionine iodide [3493-13-8]
Cat# T74497-50mg
Size : 50mg
Marca : TargetMol
S-Adenosyl-L-methionine iodide
(Synonyms: S-Adenosyl methionine iodide, AdoMet iodide, Ademetionine iodide) Copy Product InfoS-Adenosyl-L-methionine iodide is a universal methyl donor in vivo, participating in the methylation of DNA, RNA, and proteins, playing a core role in gene regulation and cellular homeostasis.
Cas No. 3493-13-8
For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Solid
Color:Yellow
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | S-Adenosyl-L-methionine iodide is a universal methyl donor in vivo, participating in the methylation of DNA, RNA, and proteins, playing a core role in gene regulation and cellular homeostasis. |
| In vitro | S-Adenosyl-L-methionine iodide (300 µM) induces apoptosis and cell cycle arrest in oral squamous cell carcinoma cells by downregulating cyclins B1, E1, and D1 [4]. It also enhances the sensitivity of cancer cells to 5-FU by modulating the expression of DNA methyltransferases (DNMTs) [5]. |
| In vivo | Oral administration of S-Adenosyl-L-methionine iodide (30 mg/kg) prevents ASD-like neurobehavioral symptoms and normalizes redox potential in mouse models [6]. It also demonstrates anti-epileptic and memory-enhancing properties by reducing oxidative stress in seizure-induced rat models [7]. |
| Synonyms | S-Adenosyl methionine iodide, AdoMet iodide, Ademetionine iodide |
| Molecular Weight | 526.35 |
| Formula | C15H23IN6O5S |
| Cas No. | 3493-13-8 |
| Smiles | O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](C[S+](CC[C@@H](C(O)=O)N)C)[C@H]1O.[I-] |
| Storage | Keep away from moisture,Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |