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> SARS-CoV-2 ORF1ab Peptide (GTGTIYTELEPPCRF)

SARS-CoV-2 ORF1ab Peptide (GTGTIYTELEPPCRF)

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Cat# VGP1588

Size : 100ug

Marca : Abcepta

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Product Information
Sequence GTGTIYTELEPPCRF
Purity >90% (HPLC-MS)
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Cellular immune response, T-cell expansion, Antigen specific T-cell stimulation, Immune monitoring, T-cell assays
Primary Accession P0DTD1
Other Accession R1AB_SARS2
Additional Information
Gene ID 43740578
Other Names Replicase polyprotein 1ab, pp1ab (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor nsp1 (Leader protein) (Non-structural protein 1, nsp1); Non-structural protein 2, nsp2 (p65 homolog); Non-structural protein 3, nsp3, EC 3.4.19.12, EC 3.4.22.- (PL2-PRO) (Papain-like proteinase, PL-PRO); Non-structural protein 4, nsp4; 3C-like proteinase, 3CL-PRO, 3CLp, EC 3.4.22.69 (Main protease, Mpro) (Non-structural protein 5, nsp5) (SARS coronavirus main proteinase); Non-structural protein 6, nsp6; Non-structural protein 7, nsp7; Non-structural protein 8, nsp8; Non-structural protein 9, nsp9; Non-structural protein 10, nsp10 (Growth factor-like peptide, GFL); RNA-directed RNA polymerase, Pol, RdRp, EC 2.7.7.48 (Non-structural protein 12, nsp12); Helicase, Hel, EC 3.6.4.12, EC 3.6.4.13 (Non-structural protein 13, nsp13); Proofreading exoribonuclease, ExoN, EC 3.1.13.- (Guanine-N7 methyltransferase) (Non-structural protein 14, nsp14); Uridylate-specific endoribonuclease, EC 3.1.-.- (NendoU) (Non-structural protein 15, nsp15); 2'-O-methyltransferase, EC 2.1.1.- (Non-structural protein 16, nsp16) ]
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name rep
Function Replicase polyprotein 1ab is a multifunctional protein involved in the transcription and replication of SARS-Cov-2 RNAs crucial to the viral life cycle. Contains the proteinases responsible for the cleavages of the polyprotein, including host translation inhibitor non-structural proteins nsp1, nsp2, nsp3, nsp4, nsp6, nsp7, nsp8, nsp9, nsp10, 3C-like proteinase, RNA-directed RNA polymerase, helicase, proofreading exoribonuclease, uridylate-specific endoribonuclease, and 2'-O-methyltransferase.
Cellular Location Cleaved proteins localize in different host cellular compartments, including membrane, cytoplasm, virally-induced cytoplasmic double-membrane vesicles, perinuclear cytoplasmic foci, and endoplasmic reticulum-Golgi intermediate compartments.