Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
What is the species homology for "SOST Antibody - C-terminal region (ARP63543_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".
How long will it take to receive "SOST Antibody - C-terminal region (ARP63543_P050)"?
This item is available "Domestic: within 24 hours delivery | International: 3-5 days".
What buffer format is "SOST Antibody - C-terminal region (ARP63543_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.". Additional format options may be available. For more information please contact info@avivasysbio.com.
What are other names for "SOST Antibody - C-terminal region (ARP63543_P050)"?
This target may also be called "CDD, VBCH, DAND6, SOST1" in publications.
What is the shipping cost for "SOST Antibody - C-terminal region (ARP63543_P050)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
What is the guarantee for "SOST Antibody - C-terminal region (ARP63543_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "SOST Antibody - C-terminal region (ARP63543_P050)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "23 kDa". Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "SOST Antibody - C-terminal region (ARP63543_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
What are positive controls for "SOST"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "SOST"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What other proteins interact with "SOST"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "SOST"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "SOST"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "SOST"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
SOST Antibody - N-terminal region (OAAB16592)
Catalog #: OAAB16592
Application: WB, IHC
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Size: 200ul
SOST Antibody - middle region (OAAB16593)
Catalog #: OAAB16593
Application: WB, IHC
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Size: 400ul
SOST Antibody - C-terminal region (OAEB03260)
Catalog #: OAEB03260
Application: IHC
Format: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
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