Surfactin [24730-31-2]

Cat# NB-64-04572-100mg

Size : 100mg

Marca : Neo Biotech


Surfactin

Catalog No. T13041 Copy Product Info
Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes, with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects.

Surfactin

Copy Product Info

Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes, with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects.

Surfactin
Cas No. 24730-31-2
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Purity:mixture
Color:White
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Product Introduction

Bioactivity
Description
Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes, with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects.
In vitro
Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. surfactin can increase the activity of amoxicillin against avian pathogenic Escherichia coli (APEC) in vitro with antimicrobial assays such as minimum inhibitory concentrations (MIC) and fractional inhibitory concentration (FIC).
In vivo
in the model of chick infection, surfactin exerted adjuvant effects with amoxicillin against APEC by lowering the numerical value of mortality and liver bacterial loads, and regulating the expression of inflammatory cytokines et al.We concluded that surfactin can act as a novel antimicrobial adjuvant with amoxicillin against AEPC infection in chicken.
Chemical Properties
Molecular Weight1036.34
FormulaC53H93N7O13
Cas No.24730-31-2
SmilesCC(C)CCCCCCCCCCCC(=O)N1[C@@H](C(O)CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C1=O
Relative Density.1.037 g/cm3 (Predicted)
Storage & Solubility Information
Storage
Solubility Information
H2O: 28.25 mg/mL (27.26 mM), Sonication is recommended.
DMSO: 257.5 mg/mL (248.47 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2 mg/mL (1.93 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM0.9649 mL4.8247 mL9.6493 mL48.2467 mL
5 mM0.1930 mL0.9649 mL1.9299 mL9.6493 mL
10 mM0.0965 mL0.4825 mL0.9649 mL4.8247 mL
20 mM0.0482 mL0.2412 mL0.4825 mL2.4123 mL
DMSO
1mg5mg10mg50mg
50 mM0.0193 mL0.0965 mL0.1930 mL0.9649 mL
100 mM0.0096 mL0.0482 mL0.0965 mL0.4825 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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