Taurochenodeoxycholic acid [516-35-8]
Cat# M11178-50mg
Size : 50mg
Marca : AbMole Bioscience
All AbMole products are for research use only, cannot be used for human consumption.
Taurochenodeoxycholate, TCDCA, 12-Deoxycholyltaurine, Chenodeoxycholyltaurine, Chenyltaurine
Quality Control & Documentation
Biological Activity
Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animal bile acids. Taurochenodeoxycholic acid induces apoptosis (apoptosis) and has a pronounced anti-inflammatory and immunomodulatory effect.
Chemical Information
| Molecular Weight | 499.7 |
| Formula | C26H45NO6S |
| CAS Number | 516-35-8 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
References
[1] Youchao Qi, et al. Molecules. Taurochenodeoxycholic Acid Increases cAMP Content via Specially Interacting with Bile Acid Receptor TGR5
[2] Lucas Zangerolamo, et al. Life Sci. The bile acid TUDCA and neurodegenerative disorders: An overview
[3] You-Chao Qi, et al. Chin J Nat Med. Taurochenodeoxycholic acid mediates cAMP-PKA-CREB signaling pathway
[4] Pavan Bhargava, et al. J Clin Invest. Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation
[5] Lei Li, et al. Molecules. Taurochenodeoxycholic Acid Inhibited AP-1 Activation via Stimulating Glucocorticoid Receptor