store at 4°C
Tween 80 [9005-65-6]
Cat# T13947-100mL
Size : 100mL
Marca : TargetMol
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Tween 80
Catalog No. T13947 CAS 9005-65-6
Tween 80 is a nonionic surfactant and emulsifier that reduces bacterial adherence and inhibits biofilm formation. Tween 80 is widely used as a co-solvent in pharmacology experiments because of its ability to enhance the solubility of compounds in the aqueous phase.
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Tween 80, CAS 9005-65-6
| Description | Tween 80 is a nonionic surfactant and emulsifier that reduces bacterial adherence and inhibits biofilm formation. Tween 80 is widely used as a co-solvent in pharmacology experiments because of its ability to enhance the solubility of compounds in the aqueous phase. |
| In vitro | METHODS: S. aureus, L. monocytogenes, and P. fluorescens were treated with Tween 80 (0.1% (v/v) in TSB), and growth curves were documented by measuring optical densities at OD600 every 20 min. RESULTS: Tween 80 increased the growth rate of S. aureus. tween 80 did not affect the growth of L. monocytogenes. the growth rate of the P. fluorescens tween 80 group was initially higher than that of the control group, but then declined again, with the maximum OD significantly lower than that of the control. [1] |
| In vivo | METHODS: To study the effect of solvents on locomotor activity in mice, Tween-80/Tween-20 (4%-64% (v/v) in saline) was administered intraperitoneally as a single injection to (BALB/c * DBA/2) F1 mice, and the locomotor activity was monitored for 12 h after the administration. RESULTS: Tween-80 significantly decreased the locomotor activity of mice at a concentration of 32%, while Tween-20 significantly decreased the locomotor activity of mice at a concentration of 16%. [2] METHODS: To detect anti-tumor activity in vivo, ATL (15-30 mg/kg in 5% DMSO + 30% PEG300 + 10% Tween 80 + 55% PBS) was injected intraperitoneally into BALB/c mice harboring human thyroid carcinoma tumor 8505C once daily for nine weeks. RESULTS: ATL inhibited the growth of 8505C cell xenografts in vivo. [3] |
| Molecular Weight | N/A |
| CAS No. | 9005-65-6 |
Storage
References and Literature
1. Nielsen CK, et al. Effects of Tween 80 on Growth and Biofilm Formation in Laboratory Media. Front Microbiol. 2016 Nov 22;7:1878. 2. Castro CA, et al. Behavioral effects of vehicles: DMSO, ethanol, Tween-20, Tween-80, and emulphor-620. Pharmacol Biochem Behav. 1995 Apr;50(4):521-6. 3. Hu Y, et al. Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway. Phytomedicine. 2023 Jan;108:154528.
Citations
1. Hu Y, Wen Q, Cai Y, et al. Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway. Phytomedicine. 2022: 154528. 2. Yang D, Fan Y, Xiong M, et al.Loss of renal tubular G9a benefits acute kidney injury by lowering focal lipid accumulation via CES1.EMBO reports.2023: e56128. 3. Guo Y, Zhu L, Duan Y, et al.Ruxolitinib induces apoptosis and pyroptosis of anaplastic thyroid cancer via the transcriptional inhibition of DRP1-mediated mitochondrial fission.Cell Death & Disease.2024, 15(2): 125.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Keywords
Tween 80 9005-65-6 Others Polysorbate80 inhibit Tween-80 Polysorbate-80 Polysorbate 80 Tween80 Inhibitor inhibitor