Reagenti e strumenti per immunologia, biologia cellulare e biologia molecolare
 
> Verbascose [546-62-3]

Verbascose [546-62-3]

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Cat# T6754-1mg

Size : 1mg

Marca : TargetMol


Verbascose

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Verbascose is an oligosaccharide and non-reducing sugar that can regulate and enhance the immune function of RAW264.7 macrophages, increasing their proliferation activity, phagocytic activity, NO release, and cytokine secretion levels, and also has the potential to regulate intestinal microecological balance.
Verbascose
Cas No. 546-62-3
For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.18%
Appearance:Solid
Color:White

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Product Introduction

Bioactivity
Description
Verbascose is an oligosaccharide and non-reducing sugar that can regulate and enhance the immune function of RAW264.7 macrophages, increasing their proliferation activity, phagocytic activity, NO release, and cytokine secretion levels, and also has the potential to regulate intestinal microecological balance.
In vitro
Method:
RAW264.7 cells were treated with different concentrations of Verbascose (25, 50, 100, 200, and 400 μg/mL) for 12, 24, 36, and 48 hours, and cell viability was assessed.
Result:
Verbascose significantly increased the viability of RAW264.7 cells in the range of 25–400 μg/mL in a time-dependent manner [1].
In vivo
Methods:
Immunosuppressed female Kunming mice were subcutaneously injected with different doses of Verbascose (30, 90, 120 mg/kg) once daily for 8 consecutive days.
Results:
Treatment with the medium dose (90 mg/kg) significantly increased the spleen index, lysozyme activity in the spleen and serum, serum hemolysin levels, and the earlap swelling rate in the delayed-type hypersensitivity (DTH) response.
Chemical Properties
Molecular Weight828.72
FormulaC30H52O26
Cas No.546-62-3
SmilesO([C@]1(CO)O[C@H](CO)[C@@H](O)[C@@H]1O)[C@H]2O[C@H](CO[C@H]3O[C@H](CO[C@H]4O[C@H](CO[C@H]5O[C@H](CO)[C@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](O)[C@H]4O)[C@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O
Relative Density.1.86g/cm3
Storage & Solubility Information
StorageStore at low temperature,Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.