Vincristine sulfate

Cat# M1892-10mg

Size : 10mg

Marca : AbMole Bioscience

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Vincristine sulfate Structure
Synonym:

leurocristine, Oncovin


Quality Control & Documentation
Biological Activity

Vincristine (leurocristine, Oncovin), sometimes abbreviated "VCR", is a kind of microtubule function inhibitor. Vincristine sulfate is the salt of an alkaloid from the flowering periwinkle plant (also known as Vinca rosea Linn). Vincristine sulfate induces apoptosis in human lymphoma cells. Vincristine binds to tubulin dimers, inhibiting assembly of microtubule structures. The IC50 and IC90 of vincristine for the 4 vaccine-associated feline sarcoma (VAFS) cell lines were between 0.005 to 0.039 µg/ml and 0.045 to 1.027 µg/ml, respectively.

Chemical Information
Molecular Weight 923.04
Formula C46H56N4O10.H2SO4
CAS Number 2068-78-2
Solubility (25°C) DMSO 80 mg/mL
Water 60 mg/mL
Storage -20°C, protect from light, sealed
References

[1] Jordan MA, et al. Cancer Res. Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro.

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Cat#
Descrizione
Cond.
Priced
NB-48-0953-10MG
 10mg