Mouse Anti-Human CD71-LE/AF
Cat# 9670-14
Size : 0.5mg
Marca : Southern Biotech
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Telefono : +1 850 650 7790
| Clone | RVS-10 |
|---|---|
| Isotype | Mouse IgG1κ |
| Isotype Control | Mouse IgG1-LE/AF (15H6) |
| Specificity | Human CD71 |
| Alternative Names | TFR, TRFR, transferrin receptor, T9 |
| Description | CD71 is a 95 kDa type II heterodimeric transmembrane glycoprotein that is the receptor for transferrin. CD71 expression is very low on resting leukocytes but is upregulated upon activation. CD71 plays a critical role in cell proliferation by controlling the supply of iron which is essential for many metabolic pathways through the binding and endocytosis of transferrin. |
| Conjugate | LE/AF (Low Endotoxin/Azide Free) |
| Buffer Formulation | Phosphate buffered saline, pH 7.4 |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C; Handle under aseptic conditions |
| Applications | Flow Cytometry – Quality tested 5 Immunocytochemistry – Reported in literature 1-3 Drug Delivery – Reported in literature 4 |
| RRID Number | AB_2797066 |
| Gene ID | 7037 (Human) |
| Gene ID Symbol | TFRC (Human) |
| Gene ID Aliases | CD71; IMD46; T9; TFR; TFR1; TR; TRFR; p90 |
| UniProt ID | P02786 (Human) |
| UniProt Name | TFR1_HUMAN (Human) |
Documentation
Technical Bulletin Safety Datasheet
Certificate of Analysis Lookup
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- 1. O'Donnell V, LaRocco M, Duque H, Baxt B. Analysis of foot-and-mouth disease virus internalization events in cultured cells. J Virol. 2005;79:8506-18. (ICC)
- 2. Keyel PA, Mishra SK, Roth R, Heuser JE, Watkins SC, Traub LM. A single common portal for clathrin-mediated endocytosis of distinct cargo governed by cargo-selective adaptors. Mol Biol Cell. 2006;17:4300-17. (ICC)
- 3. Di Pucchio T, Chatterjee B, Smed-Sörensen A, Clayton S, Palazzo A, Montes M, et al. Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I. Nat Immunol. 2008;9:551-7. (ICC)
- 4. Patil R, Portilla-Arias J, Ding H, Inoue S, Konda B, Hu J. Temozolomide delivery to tumor cells by a multifunctional nano vehicle based on poly(β-L-malic acid). Pharm Res. 2010;27:2317-29. (Drug Delivery)
- 5. Seiffert M, Cant C, Chen Z, Rappold I, Brugger W, Kanz L, et al. Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47. Blood. 1999;94:3633-43. (FC)