Neuroligin 1 antibody
Cat# orb150876-100ug
Size : 100ug
Marca : Biorbyt
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Neuroligin 1 antibody
Catalog Number: orb150876
| Catalog Number | orb150876 |
|---|---|
| Category | Antibodies |
| Description | Mouse monoclonal to Neuroligin 1 (ATTO-488). Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord.. |
| Species/Host | Mouse |
| Clonality | Monoclonal |
| Clone Number | S97A-31 |
| Tested applications | ICC, IHC, WB |
| Reactivity | Human, Mouse, Rat |
| Isotype | IgG1 |
| Immunogen | Fusion protein amino acids 718-843 (cytoplasmic C-terminus) of rat Neuroligin-1. Mouse: 99% identity (125/126 amino acids identical). Human: 99% identity (125/126 amino acids identical) > 40% identity with Neuroligin-2 and -3. |
| Concentration | 1 mg/ml |
| Dilution range | WB (1:1000), ICC/IF (1:100) |
| Conjugation | ATTO-488 |
| MW | 120kDa |
| Target | Neuroligin 1 |
| Entrez | 116647 |
| UniProt ID | Q62765 |
| NCBI | NP_446320.1 |
| Storage | Conjugated antibodies should be stored at 4°C |
| Buffer/Preservatives | PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated |
| Alternative names | NLG 1 antibody, KIAA1070 antibody, MGC45115 antibo |
| Note | For research use only |
| Application notes | 2 µg/ml of SMC-463 was sufficient for detection of Neuroligin-1 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Expiration Date | 12 months from date of receipt. |