21-Deoxycortisol-d8 [2479914-04-8]

Cat# NB-64-92542-5mg

Size : 5mg

Marca : Neo Biotech


21-Deoxycortisol-D8

Catalog No. TMID-0112 Copy Product Info
21-Deoxycortisol-D8 isol-D8 is a deuterated compound of 21-Deoxycortisol. 21-Deoxycortisol (T36915) has a CAS number of 641-77-0. 21-Deoxycortisol (T36915) is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies.

21-Deoxycortisol-D8

Copy Product Info

21-Deoxycortisol-D8 isol-D8 is a deuterated compound of 21-Deoxycortisol. 21-Deoxycortisol (T36915) has a CAS number of 641-77-0. 21-Deoxycortisol (T36915) is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies.

21-Deoxycortisol-D8
Cas No. 2479914-04-8

Product Introduction

Bioactivity
Description
21-Deoxycortisol-D8 isol-D8 is a deuterated compound of 21-Deoxycortisol. 21-Deoxycortisol (T36915) has a CAS number of 641-77-0. 21-Deoxycortisol (T36915) is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies.
Chemical Properties
Molecular Weight354.51
FormulaC21H22D8O4
Cas No.2479914-04-8
SmilesC[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(C(C3)([2H])[2H])=C(C(=O)C(C4)([2H])[2H])[2H])([C@@H](O)C1)14)14)(CC[C@@]2(C(C([2H])([2H])[2H])=O)O)14
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.