| CAS-Number: | 136977-42-9 |
|---|---|
| Molecular Weight: | 527,5 |
| Empirical Formula: | C29H25N3O7 |
| Absorption [nm]: | 548 ± 3 |
| Emission [nm]: | 570 ± 3 |
| ε [M-1 cm-1]: | >78 000 |
| Buffer System for Fluorescence Readings: | PBS, pH 7.4 |
| Solubility: | Acetonitril, DMF, DMSO |
| Appearance (colour): | violett |
| Appearance (form): | solid (powder) |
| Storage: | - 20 °C. Keep dry! Keep away from light, especially in solution! |
| Trade name: | 6-Carboxytetramethylrhodamine, succinimidylester, single isomer; 6-TAMRA-SE; 6-TAMRA succinimidyl ester, singel isomer |
| Reactive Moiety: | NHS ester, reacts with 1° amines to form a stable amide linkage |
This single isomer amine-reactive red fluorescent derivatization reagent may be used for covalent labeling of proteins and alkylamino modified nucleic acids.
The fluorescence quantum yield of TAMRA conjugates is about one-fourth that of fluorescein conjugates. Nevertheless, TAMRA conjugates often appear brighter than the corresponding fluorescein conjugates due to the fact that TAMRA is readily excited by the 546 nm spectral line from mercury-arc lamps used in most fluorescence microscopes and is intrinsically more photostable than fluorescein. TAMRA is also efficiently excited by the 543 nm spectral line of the green He-Ne laser.
6-TAMRA-SE
Hazard Classifications
Skin irritation, Category 2 (Skin Irrit. 2)
Eye irritation, Category 2 (Eye Irrit. 2)
Specific target organ toxicity - single exposure, Category 3 (STOT SE 3)
Hazard Statements
| H315 | Causes skin irritation. |
| H319 | Causes serious eye irritation. |
| H335 | May cause respiratory irritation. |
Precautionairy Statements
| P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
| P262 | Do not get in eyes, on skin, or on clothing. |
| P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
| P302+P352 | IF ON SKIN: Wash with plenty of water/… |
| P305+P351+P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
Signal Word
Warning
WGK
WGK 3
Storage Class Code
11 - Flammable solids
ADR, RID (road and railroad)
Not dangerous goods
IATA-DGR (transport by air)
Not dangerous goods
IMDG-Code (transport by sea)
Not dangerous goods
Gefahreneinstufungen
Ätz-/Reizwirkung auf die Haut, Kategorie 2 (Skin Irrit. 2)
Schwere Augenschädigung/Augenreizung, Kategorie 2 (Eye Irrit. 2)
Spezifische Zielorgan-Toxizität (einmalige Exposition), Kategorie 3 (STOT SE 3)
Gefahrenhinweise - H-Sätze
| H315 | Verursacht Hautreizungen. |
| H319 | Verursacht schwere Augenreizung. |
| H335 | Kann die Atemwege reizen. |
Sicherheitshinweise - P-Sätze
| P261 | Einatmen von Staub/Rauch/Gas/Nebel/Dampf/Aerosol vermeiden. |
| P262 | Nicht in die Augen, auf die Haut oder auf die Kleidung gelangen lassen. |
| P280 | Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz/Gehörschutz/… tragen. |
| P302+P352 | BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/… waschen. |
| P305+P351+P338 | BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
Signalwort
Achtung
WGK
WGK 3
Lagerklasse
11 - Entzündbare Feststoffe
ADR, RID (Strasse und Eisenbahn)
Kein Gefahrgut
IATA-DGR (Luftverkehr)
Kein Gefahrgut
IMDG (Seeschiffverkehr)
Kein Gefahrgut