Etimizol [64-99-3]
Cat# HY-13918-10mg
Size : 10mg
Marca : MedChemExpress
Etimizol(Ethymisole; Antiffine; Ethylnorantifein) was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain).
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Etimizol Chemical Structure
CAS No. : 64-99-3
This product is a controlled substance and not for sale in your territory.
Description |
Etimizol(Ethymisole; Antiffine; Ethylnorantifein) was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain). |
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In Vivo |
The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series. Etimizol (Ethymisole) did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement [1]. After administration of Etimizol (Ethymisole) at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min, respectively, with mean standard deviation being 3.1 and 0.8, respectively [2]. Extracellular application of 5--10 mM/L Etimizol (Ethymisole) exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude [3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Masse moléculaire |
210.23 |
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Formule |
C9H14N4O2 |
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CAS No. |
64-99-3 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
O=C(C1=C(C(NC)=O)N(CC)C=N1)NC |
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Livraison | Room temperature in continental US; may vary elsewhere. |
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Stockage |
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Solvant et solubilité |
In Vitro:
Ethanol : ≥ 33.33 mg/mL (158.54 mM) *"≥" means soluble, but saturation unknown. Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
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Pureté et documentation |
Purity: 99.95% |
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Références |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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Ethanol | 1 mM | 4.7567 mL | 23.7835 mL | 47.5670 mL | 118.9174 mL |
5 mM | 0.9513 mL | 4.7567 mL | 9.5134 mL | 23.7835 mL | |
10 mM | 0.4757 mL | 2.3783 mL | 4.7567 mL | 11.8917 mL | |
15 mM | 0.3171 mL | 1.5856 mL | 3.1711 mL | 7.9278 mL | |
20 mM | 0.2378 mL | 1.1892 mL | 2.3783 mL | 5.9459 mL | |
25 mM | 0.1903 mL | 0.9513 mL | 1.9027 mL | 4.7567 mL | |
30 mM | 0.1586 mL | 0.7928 mL | 1.5856 mL | 3.9639 mL | |
40 mM | 0.1189 mL | 0.5946 mL | 1.1892 mL | 2.9729 mL | |
50 mM | 0.0951 mL | 0.4757 mL | 0.9513 mL | 2.3783 mL | |
60 mM | 0.0793 mL | 0.3964 mL | 0.7928 mL | 1.9820 mL | |
80 mM | 0.0595 mL | 0.2973 mL | 0.5946 mL | 1.4865 mL | |
100 mM | 0.0476 mL | 0.2378 mL | 0.4757 mL | 1.1892 mL |
Etimizol Related Classifications
- Others
- Others